ArticleNature2023
A cross-species proteomic map reveals neoteny of human synapse development.
Open access · greenAbstract readComparative Study
In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
10.8field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
53 citing papers in PubMed, 70 citations in OpenAlex.
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- A single-cell transcriptomic atlas of the periventricular proliferative zone in the late gestation fetal brain in the pigtail macaque.Frontiers in neuroscience · 2026Article
- The Role of Astrocyte-Neuron Interactions in Shaping Neuronal Maturation during Human Brain Development.Computational and structural biotechnology journal · 2026Article
- Human-specific features of the cerebellum and ZP2-regulated synapse development.bioRxiv : the preprint server for biology · 2025Article
- A General Principle of Neuronal Evolution Reveals a Human-Accelerated Neuron Type Potentially Underlying the High Prevalence of Autism in Humans.Molecular biology and evolution · 2025Article
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors at 5 institutions in 2 countries.
Li WangThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA. Li.Wang@ucsf.edu.ORCID 0000-0001-9510-6294
Kaifang PangJan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX, USA.
Li ZhouThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-8170-4549
Arantxa Cebrián-SillaThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Susana González-GraneroLaboratory of Comparative Neurobiology, Cavanilles Institute of Biodiversity and Evolutionary Biology, University of Valencia and CIBERNED, Valencia, Spain.
Shaohui WangThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Qiuli BiThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Matthew L WhiteThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Brandon HoThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Jiani LiGilead Sciences, Foster City, CA, USA.
Tao LiThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-9174-1271
Yonatan PerezThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Eric J HuangDepartment of Pathology, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-5381-3801
Ethan A WinklerDepartment of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.
Mercedes F ParedesThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0003-2503-1447
Rothem KovnerDepartment of Neuroscience, Yale School of Medicine, Yale University, New Haven, CT, USA.
Nenad SestanDepartment of Neuroscience, Yale School of Medicine, Yale University, New Haven, CT, USA.ORCID 0000-0003-0966-9619
Alex A PollenThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0003-3263-8634
Pengyuan LiuDepartment of Chemistry, University of Massachusetts Lowell, Lowell, MA, USA.
Jingjing LiThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0001-6025-9522
Xianhua PiaoThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0001-7540-6767
José Manuel García-VerdugoLaboratory of Comparative Neurobiology, Cavanilles Institute of Biodiversity and Evolutionary Biology, University of Valencia and CIBERNED, Valencia, Spain.ORCID 0000-0001-9872-6499
Arturo Alvarez-BuyllaThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Zhandong LiuJan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX, USA.
Arnold R KriegsteinThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA. Arnold.Kriegstein@ucsf.edu.ORCID 0000-0001-5742-2990
University of California, San Francisco · USBaylor College of Medicine · USUniversitat de València · ESYale University · USUniversity of Massachusetts Lowell · US
Funding
Regulation of Cellular Pathwaysin Human Brain DevelopmentP01NS083513 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PIAO, XIANHUA · 2014 to 2024
$12.6MNEUROGENESIS IN THE ADULT VERTEBRATE BRAINR01NS028478 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ALVAREZ-BUYLLA, ARTURO · 1996 to 2024
$8.6MDevelopment and Expansion of the Human Cerebral CortexR35NS097305 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KRIEGSTEIN, ARNOLD · 2017 to 2024
$8.5MDevelopmental cell census of human and non-human primate brainU01MH124619 · NIMH · YALE UNIVERSITY · PI SESTAN, NENAD · 2020 to 2022
$3.3MIdentification of Genetic and Molecular Bases of Derived Phenotypes in Primate Brain DevelopmentR01HG010898 · NHGRI · YALE UNIVERSITY · PI SANTPERE BARO, GABRIEL, SESTAN, NENAD · 2020 to 2023
$2.2MLTQ XL Linear Quadrupole Ion Trap Mass SpectrometerS10RR025622 · NCRR · UNIVERSITY OF CALIFORNIA BERKELEY · PI KOHLSTAEDT, LORI · 2009 to 2009
$463kIdentifying mechanisms ofsynapse maturation at neuronal subtype resolutionK99MH131832 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WANG, LI · 2023 to 2024
$182kNCRR NIH HHS S10 RR025622NHGRI NIH HHS R01 HG010898NIMH NIH HHS K99 MH131832NIMH NIH HHS U01 MH124619NINDS NIH HHS P01 NS083513NINDS NIH HHS R01 NS028478NINDS NIH HHS R35 NS097305
Abstract
The molecular mechanisms and evolutionary changes accompanying synapse development are still poorly understood
Indexed as
ProteomicsSynapsesAdolescentAnimalsChildChild, PreschoolCognitionDendritic SpinesGestational AgeHumansInfantInfant, NewbornMacacaMiceNeuronsPost-Synaptic DensityRho Guanine Nucleotide Exchange Factors
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.