ArticleNature communications2023
Variation in spatial dependencies across the cortical mantle discriminates the functional behaviour of primary and association cortex.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Spatial Collinearity Constrains Multivariate Molecular-Enriched Network Estimation.Human brain mapping · 2026Article
- Opportunities and pitfalls of data contextualization in neuroimaging.Nature reviews. Neuroscience · 2026Review
- Individual differences reveal distinct age and pubertal contributions to the refinement of the functional cortical hierarchy during adolescence.bioRxiv : the preprint server for biology · 2026Article
- Intrinsic cortical geometry is associated with individual differences in local functional organization.Research square · 2026Article
- Bridging glucose metabolism and intrinsic functional organization of the human cortex.Communications biology · 2026Article
- Robust FDR Control for Neuroimaging-based Classification via Knockoffs.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2026Article
- Exploring atypical spatial-functional coupling in adolescent autism spectrum disorder: insights from neurodevelopment and transcriptomic architecture.Frontiers in neuroscience · 2026Article
- Patterned wireless transcranial optogenetics generates artificial perception.Nature neuroscience · 2026Article
- Geometric constraints on the architecture of mammalian cortical connectomes.bioRxiv : the preprint server for biology · 2025Article
- Distinct genetic underpinnings of inter-individual differences in the sensorimotor-association axis of cortical organisation.bioRxiv : the preprint server for biology · 2025Article
- The spatial layout of antagonistic brain regions is explicable based on geometric principles.Communications biology · 2025Article
- Stimulation mapping and whole-brain modeling reveal gradients of excitability and recurrence in cortical networks.Nature communications · 2025Article
- Understanding the Link Between Functional Profiles and Intelligence Through Dimensionality Reduction and Graph Analysis.Human brain mapping · 2025Article
- Structure-function relationships across scales: implications for atlases.Frontiers in neuroscience · 2025Article
- The effect of spherical projection on spin tests for brain maps.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Gradients of Brain Organization: Smooth Sailing from Methods Development to User Community.Neuroinformatics · 2024Review
- Sex differences in functional cortical organization reflect differences in network topology rather than cortical morphometry.Nature communications · 2024Article
- Connectome reorganization associated with temporal lobe pathology and its surgical resection.Brain : a journal of neurology · 2024Article
- The Brain's Topographical Organization Shapes Dynamic Interaction Patterns That Support Flexible Behavior Based on Rules and Long-Term Knowledge.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Multimodal analysis of disease onset in Alzheimer's disease using Connectome, Molecular, and genetics data.NeuroImage. Clinical · 2024Article
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Authors and funding
14 authors.
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Abstract
Recent theories of cortical organisation suggest features of function emerge from the spatial arrangement of brain regions. For example, association cortex is located furthest from systems involved in action and perception. Association cortex is also 'interdigitated' with adjacent regions having different patterns of functional connectivity. It is assumed that topographic properties, such as distance between regions, constrains their functions, however, we lack a formal description of how this occurs. Here we use variograms, a quantification of spatial autocorrelation, to profile how function changes with the distance between cortical regions. We find function changes with distance more gradually within sensory-motor cortex than association cortex. Importantly, systems within the same type of cortex (e.g., fronto-parietal and default mode networks) have similar profiles. Primary and association cortex, therefore, are differentiated by how function changes over space, emphasising the value of topographical features of a region when estimating its contribution to cognition and behaviour.
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