Evidence map›Paper›PMID 37704548›Full record

ArticleTrends in immunology2023

Over but not gone: lingering epigenetic effects of COVID-19.

Brandon T Tran, Ruoqiong Cao, Katherine Y King

Open access · greenAbstract read
In one paragraph

Article in Trends in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 64% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Brandon T TranProgram in Cancer and Cell Biology, Graduate School of Biomedical Sciences, Baylor College of Medicine, Houston, TX, USA.
Ruoqiong CaoProgram in Immunology and Microbiology, Graduate School of Biomedical Sciences, Baylor College of Medicine, Houston, TX, USA.
Katherine Y KingProgram in Cancer and Cell Biology, Graduate School of Biomedical Sciences, Baylor College of Medicine, Houston, TX, USA; Program in Immunology and Microbiology, Graduate School of Biomedical Sciences, Baylor College of Medicine, Houston, TX, USA; Department of Pediatrics, Division of Infectious Disease, Baylor College of Medicine, Houston, TX, USA. Electronic address: Kyk@bcm.edu.
Baylor College of Medicine · US

Funding

Project 3: Contribution of inflammation and DNA damaging factors to clonal expansion and malignant transformation in a community cohort of older adultsP01CA265748 · NCI · BAYLOR COLLEGE OF MEDICINE · PI ELIZABETH A. PLATZ · 2022 to 2026
$13.6M
Training In Cell and Gene TherapyT32HL092332 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI MALCOLM K. BRENNER, Bruno Di Stefano · 2008 to 2026
$6.9M
Impact of Infection and Inflammation on Primitive HematopoiesisR35HL155672 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI Katherine Yudeh King · 2021 to 2026
$5.1M
Microbiota-dependent regulation of primitive hematopoiesesR01AI141716 · NIAID · WASHINGTON UNIVERSITY · PI BALDRIDGE, MEGAN T · 2019 to 2023
$2.3M
Epigenetic modification of hematopoietic stem and progenitor cells in inflammation-induced differentiationF31HL164287 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI TRAN, BRANDON T · 2022 to 2024
$143k
NCI NIH HHS P01 CA265748NHLBI NIH HHS F31 HL164287NHLBI NIH HHS R35 HL155672NHLBI NIH HHS T32 HL092332NIAID NIH HHS R01 AI141716
6 · The paper itself

Abstract

'Long COVID' affects nearly one in five adults who have had coronavirus disease 2019 (COVID-19), yet the mechanisms underlying this disorder remain poorly understood. In a new study, Cheong et al. show that the epigenetic and transcriptional state of myeloid immune cells and their progenitors are durably altered in patients following severe COVID-19.

Indexed as

COVID-19AdultEpigenesis, GeneticHumansPost-Acute COVID-19 SyndromeSARS-CoV-2

Identifiers

PMID37704548
PMCPMC10543559
OpenAlexW4386607453

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.