Evidence map›Paper›PMID 37704489›Full record

ReviewTrends in biochemical sciences2023

Using light to drive energy transduction in metazoan aging.

Vaibhav Tiwary, Anne-Marie Galow, Andrew P Wojtovich, Shahaf Peleg

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Trends in biochemical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Vaibhav TiwaryResearch Group Epigenetics, Metabolism, and Longevity, Research Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.
Anne-Marie GalowInstitute for Genome Biology, Research Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.
Andrew P WojtovichUniversity of Rochester Medical Center, Department of Anesthesiology and Perioperative Medicine, 575 Elmwood Avenue, Rochester, NY 14642, USA. Electronic address: andrew_wojtovich@urmc.rochester.edu.
Shahaf PelegResearch Group Epigenetics, Metabolism, and Longevity, Research Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany. Electronic address: peleg@fbn-dummerstorf.de.
Research Institute for Farm Animal Biology (FBN) · DEUniversity of Rochester Medical Center · US

Funding

Mitochondrial ROS Microdomains and Neuronal IschemiaR01NS092558 · NINDS · UNIVERSITY OF ROCHESTER · PI WOJTOVICH, ANDREW PHILLIP · 2015 to 2025
$3.7M
Mitochondrial Energy Sensing and Neuronal IschemiaR01NS115906 · NINDS · UNIVERSITY OF ROCHESTER · PI Andrew P Wojtovich · 2020 to 2026
$3.0M
Multimodal control of mitochondrial energetics to shape biological agingR56AG082916 · NIA · UNIVERSITY OF ROCHESTER · PI BITTO, ALESSANDRO, WOJTOVICH, ANDREW PHILLIP · 2023 to 2023
$316k
NIA NIH HHS R56 AG082916NINDS NIH HHS R01 NS092558NINDS NIH HHS R01 NS115906
6 · The paper itself

Abstract

Mitochondrial dysfunction is a central hallmark of aging and energy transduction is a promising target for longevity interventions. New research suggests that interventions in how energy is transduced could benefit healthy longevity. Here, we propose using light as an alternative energy source to fuel mitochondria and increase metazoan lifespan.

Indexed as

AgingEnergy MetabolismLightMitochondriaAnimalsHumansLongevitybioenergeticslifespanmetabolismmitochondriaoptogeneticsproton pump

Identifiers

PMID37704489
PMCPMC10592090
OpenAlexW4386595180

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.