Evidence map›Paper›PMID 37704382›Full record

ArticleJournal of breast cancer2023

Estradiol-Induced Epithelial to Mesenchymal Transition and Migration Are Inhibited by Blocking c-Src Kinase in Breast Cancer Cell Lines.

Javier E Jiménez-Salazar, Rene M Rivera-Escobar, Rebeca Damián-Ferrara, Juan Maldonado-Cubas, Catalina Rincón-Pérez, Rosario Tarragó-Castellanos, Pablo Damián-Matsumura

Open access · goldAbstract read
In one paragraph

Article in Journal of breast cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Javier E Jiménez-SalazarDepartment of Biology of Reproduction, Biological Sciences and Health Division (DCBS), Autonomous Metropolitan University (UAM), Mexico City, México.ORCID https://orcid.org/0000-0003-1421-3720
Rene M Rivera-EscobarDepartment of Biology of Reproduction, Biological Sciences and Health Division (DCBS), Autonomous Metropolitan University (UAM), Mexico City, México.ORCID https://orcid.org/0000-0003-1730-3991
Rebeca Damián-FerraraMonterrey Institute of Technology and Higher Education (ITESM), School of Engineering and Sciences, Monterrey, México.ORCID https://orcid.org/0000-0003-0679-6786
Juan Maldonado-CubasFaculty of Engineering, Universidad La Salle México, Mexico City, México.ORCID https://orcid.org/0000-0002-5981-8355
Catalina Rincón-PérezEscuela Militar de Graduados de Sanidad, Secretaría de la Defensa Nacional (SEDENA), Mexico City, México.ORCID https://orcid.org/0000-0001-7319-0771
Rosario Tarragó-CastellanosDepartment of Biology of Reproduction, Biological Sciences and Health Division (DCBS), Autonomous Metropolitan University (UAM), Mexico City, México.ORCID https://orcid.org/0000-0002-2689-2524
Pablo Damián-MatsumuraDepartment of Biology of Reproduction, Biological Sciences and Health Division (DCBS), Autonomous Metropolitan University (UAM), Mexico City, México. pdamian@izt.uam.mx.ORCID https://orcid.org/0000-0003-4815-2516
Universidad Autónoma Metropolitana · MXHospital Central Militar · MXTecnológico de Monterrey · MXUniversidad La Salle · MX

Funding

DCBS-UAM
6 · The paper itself

Abstract

purposeThe epithelial-to-mesenchymal transition (EMT) is the main event that favors cell migration and metastasis in breast cancer. Previously, we demonstrated that 1 nM estradiol (E

methodsThe present work highlights the central role of c-Src in the initiation of metastasis, induced by E

resultsTreatment with E

conclusionThe present study demonstrate that E

Indexed as

Adherens JunctionsReceptors, EstrogenSignal TransductionSrc-Family KinasesTight Junctions

Identifiers

PMID37704382
PMCPMC10625871
OpenAlexW4386184479

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.