ArticleJournal of breast cancer2023
Prognostic Implication of Focal Breast Edema on Preoperative Breast Magnetic Resonance Imaging in Breast Cancer Patients.
Article in Journal of breast cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed.
- Breast edema score as a biomarker of tumor aggressiveness and its predictive value for neoadjuvant chemotherapy response.European radiology · 2026Article
- Magnetic resonance imaging as a non-invasive breast cancer tool - the relevance of breast edema score: A retrospective study.World journal of radiology · 2026Article
- Role of breast edema in predicting complete response to neoadjuvant chemotherapy in clinical axillary-positive breast cancer.Japanese journal of radiology · 2026Article
- Personalized Breast Cancer Prognosis Using a Model Based on MRI and Clinicopathological Variables.Journal of imaging informatics in medicine · 2026Article
- Multi-sequence MRI-based nomogram for prediction of human epidermal growth factor receptor 2 expression in breast cancer.Heliyon · 2025Article
- The combination of focal breast edema and adjacent vessel sign to assess the behavior of mass-type invasive ductal carcinoma.BMC medical imaging · 2024Article
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10 authors.
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Abstract
purposeIn this study, we investigated the prognostic implications of focal breast edema on preoperative breast magnetic resonance imaging (MRI) in patients with breast cancer.
methodsData of 899 patients with breast cancer at a single institution were retrospectively analyzed. The patients were divided into an edema-positive group (EPG) and an edema-negative group (ENG) based on the presence of peritumoral, prepectoral, or subcutaneous edema. Two radiologists evaluated the presence or absence of focal edema and its subtypes on preoperative breast MRI. Clinicopathologic characteristics and survival outcomes were compared between the two groups and among the three subtypes using Pearson's χ² test, Kaplan-Meier estimator, and Cox proportional hazards model.
resultsThere were 399 (44.4%) and 500 (55.6%) patients in the EPG and ENG, respectively. The EPG showed significantly higher rates of axillary lymph node metastasis (55.6% vs. 19.2%,
conclusionFocal breast edema on preoperative breast MRI implies a higher possibility of LVI and axillary lymph node metastasis, which can lead to a poor prognosis. A detailed description of focal breast edema, especially subcutaneous edema, on preoperative breast MRI may provide prognostic predictions. More intensive surveillance is required for patients with breast cancer and focal preoperative breast edema.
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