Evidence map›Paper›PMID 37704037›Full record

ArticleNature2023

Uncovering new families and folds in the natural protein universe.

Janani Durairaj, Andrew M Waterhouse, Toomas Mets, Tetiana Brodiazhenko, Minhal Abdullah, Gabriel Studer, Gerardo Tauriello, Mehmet Akdel, Antonina Andreeva, Alex Bateman and 4 more

Abstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Scalable homology detection with ERAST.Nature biotechnology · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Navigating the conjugated metabolome.bioRxiv : the preprint server for biology · 2026
    Article
  16. Article
  17. Article
  18. Exploring the protein universe with distant similarity detection methods.Protein science : a publication of the Protein Society · 2026
    Review
  19. Article
  20. Review

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Janani DurairajBiozentrum, University of Basel, Basel, Switzerland.ORCID 0000-0002-1698-4556
Andrew M WaterhouseBiozentrum, University of Basel, Basel, Switzerland.ORCID 0009-0004-5717-6063
Toomas MetsInstitute of Technology, University of Tartu, Tartu, Estonia.
Tetiana BrodiazhenkoInstitute of Technology, University of Tartu, Tartu, Estonia.
Minhal AbdullahInstitute of Technology, University of Tartu, Tartu, Estonia.ORCID 0000-0002-6018-314X
Gabriel StuderBiozentrum, University of Basel, Basel, Switzerland.
Gerardo TaurielloBiozentrum, University of Basel, Basel, Switzerland.ORCID 0000-0002-5921-7007
Mehmet AkdelVantAI, New York, NY, USA.
Antonina AndreevaEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK.ORCID 0000-0002-0450-0091
Alex BatemanEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK.ORCID 0000-0002-6982-4660
Tanel TensonInstitute of Technology, University of Tartu, Tartu, Estonia.ORCID 0000-0002-0260-3601
Vasili HauryliukInstitute of Technology, University of Tartu, Tartu, Estonia.ORCID 0000-0003-2389-5057
Torsten SchwedeBiozentrum, University of Basel, Basel, Switzerland. torsten.schwede@unibas.ch.ORCID 0000-0003-2715-335X
Joana PereiraBiozentrum, University of Basel, Basel, Switzerland. joana.pereira@unibas.ch.ORCID 0000-0002-5588-6588

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We are now entering a new era in protein sequence and structure annotation, with hundreds of millions of predicted protein structures made available through the AlphaFold database

Indexed as

Databases, ProteinDeep LearningMolecular Sequence AnnotationProtein FoldingProteinsStructural Homology, ProteinAmino Acid SequenceInternetProteins

Identifiers

PMID37704037
PMCPMC10584680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.