Evidence map›Paper›PMID 37703852›Full record

ArticleJournal of natural products2023

Cannabidiol Inhibits the Proliferation and Invasiveness of Prostate Cancer Cells.

Eve O'Reilly, Karima Khalifa, Joanne Cosgrave, Haleema Azam, Maria Prencipe, Jeremy C Simpson, William M Gallagher, Antoinette S Perry

Open access · hybridAbstract read
In one paragraph

Article in Journal of natural products, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Eve O'ReillyUCD School of Biology and Environmental Science, University College Dublin, Dublin D04 C1P1, Ireland.
Karima KhalifaUCD School of Biology and Environmental Science, University College Dublin, Dublin D04 C1P1, Ireland.
Joanne CosgraveUCD School of Biology and Environmental Science, University College Dublin, Dublin D04 C1P1, Ireland.ORCID 0000-0001-5192-7437
Haleema AzamCancer Biology and Therapeutics Laboratory, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin D04 C1P1, Ireland.
Maria PrencipeCancer Biology and Therapeutics Laboratory, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin D04 C1P1, Ireland.
Jeremy C SimpsonUCD School of Biology and Environmental Science, University College Dublin, Dublin D04 C1P1, Ireland.ORCID 0000-0002-7956-7805
William M GallagherCancer Biology and Therapeutics Laboratory, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin D04 C1P1, Ireland.
Antoinette S PerryUCD School of Biology and Environmental Science, University College Dublin, Dublin D04 C1P1, Ireland.
University College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is the fifth leading cause of cancer death in men, responsible for over 375,000 deaths in 2020. Novel therapeutic strategies are needed to improve outcomes. Cannabinoids, chemical components of the cannabis plant, are a possible solution. Preclinical evidence demonstrates that cannabinoids can modulate several cancer hallmarks of many tumor types. However, the therapeutic potential of cannabinoids in prostate cancer has not yet been fully explored. The aim of this study was to investigate the antiproliferative and anti-invasive properties of cannabidiol (CBD) in prostate cancer cells

Indexed as

CannabidiolProstatic HyperplasiaProstatic NeoplasmsCell ProliferationHumansMaleProstateCannabidiol

Identifiers

PMID37703852
PMCPMC10521019
OpenAlexW4386697884

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.