Evidence map›Paper›PMID 37702953›Full record

ArticleEMBO reports2023

CryoET shows cofilactin filaments inside the microtubule lumen.

Camilla Ventura Santos, Stephen L Rogers, Andrew P Carter

Open access · hybridAbstract read
In one paragraph

Article in EMBO reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Molecular architecture of Influenza A virions.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Camilla Ventura SantosMRC Laboratory of Molecular Biology, Cambridge, UK.ORCID 0000-0002-4406-5151
Stephen L RogersDepartment of Biology and Integrative Program for Biological and Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0002-3941-9912
Andrew P CarterMRC Laboratory of Molecular Biology, Cambridge, UK.ORCID 0000-0001-7292-5430
MRC Laboratory of Molecular Biology · GBUniversity of North Carolina at Chapel Hill · US

Funding

Identification of proteins that structurally couple epidermal cells to somatosensory neuronsR21NS125795 · NINDS · UNIVERSITY OF WASHINGTON · PI PARRISH, JAY Z, ROGERS, STEPHEN · 2021 to 2021
$442k
Medical Research Council MC_UP_A025_1011Medical Research Council MRC_UP_A025_1011NINDS NIH HHS R21 NS125795Wellcome Trust 210711/Z/18/Z
6 · The paper itself

Abstract

Cytoplasmic microtubules are tubular polymers that can harbor small proteins or filaments inside their lumen. The identities of these objects and mechanisms for their accumulation have not been conclusively established. Here, we used cryogenic electron tomography of Drosophila S2 cell protrusions and found filaments inside the microtubule lumen, which resemble those reported recently in human HAP1 cells. The frequency of these filaments increased upon inhibition of the sarco/endoplasmic reticulum Ca

Indexed as

Actin CytoskeletonCytoskeletonActin Depolymerizing FactorsActinsHumansMicrotubulesActin Depolymerizing FactorsActinscofilactincryoETluminal filamentsmicrotubules

Identifiers

PMID37702953
PMCPMC10626427
OpenAlexW4386704679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.