Evidence map›Paper›PMID 37702872›Full record

ArticleThe international journal of cardiovascular imaging2022

Atherosclerotic plaque characteristics on quantitative coronary computed tomography angiography associated with ischemia on positron emission tomography in diabetic patients.

Vasileios Kamperidis, Michiel A de Graaf, Valtteri Uusitalo, Antti Saraste, Jurriën H Kuneman, Inge J van den Hoogen, Juhani Knuuti, Jeroen J Bax

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The international journal of cardiovascular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Vasileios KamperidisDepartment of Cardiology, Heart Lung Centre, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.ORCID http://orcid.org/0000-0001-8424-6718
Michiel A de GraafDepartment of Cardiology, Heart Lung Centre, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.
Valtteri UusitaloTurku PET Centre, University of Turku, Turku, Finland.
Antti SarasteTurku PET Centre, University of Turku, Turku, Finland.
Jurriën H KunemanDepartment of Cardiology, Heart Lung Centre, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.
Inge J van den HoogenDepartment of Cardiology, Heart Lung Centre, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.
Juhani KnuutiTurku PET Centre, University of Turku, Turku, Finland.
Jeroen J BaxDepartment of Cardiology, Heart Lung Centre, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, P.O. Box 9600, 2300 RC, Leiden, The Netherlands. J.J.Bax@lumc.nl.
Leiden University · NLUniversity of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with diabetes mellitus (DM) may show diffuse coronary artery atherosclerosis on coronary computed tomography angiography (CTA). The present study aimed at quantification of atherosclerotic plaque with CTA and its association with myocardial ischemia on positron emission tomography (PET) in DM patients. Of 922 symptomatic outpatients without previously known coronary artery disease who underwent CTA, 115 with DM (mean age 65 ± 8 years, 58% male) who had coronary atherosclerosis and underwent both quantified CTA (QCTA) and PET were included in the study. QCTA analysis was performed on a per-vessel basis and the most stenotic lesion of each vessel was considered. Myocardial ischemia on PET was based on absolute myocardial blood flow at stress ≤ 2.4 ml/g/min. Of the 345 vessels included in the analysis, 135 (39%) had flow-limiting stenosis and were characterized by having longer lesions, higher plaque volume, more extensive plaque burden and higher percentage of dense calcium (37 ± 22% vs 28 ± 22%, p = 0.001). On univariable analysis, QCTA parameters indicating the degree of stenosis, the plaque extent and composition were associated with presence of ischemia. The addition of the QCTA degree of stenosis parameters (x

Indexed as

Coronary Artery DiseaseDiabetes MellitusMyocardial IschemiaPlaque, AtheroscleroticAgedComputed Tomography AngiographyConstriction, PathologicCoronary AngiographyFemaleHumansIschemiaMaleMiddle AgedPositron-Emission TomographyPredictive Value of TestsCoronary CTACoronary plaque quantificationDiabetes mellitusMyocardial ischemiaPET

Identifiers

PMID37702872
PMCPMC10499720
OpenAlexW4229378242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.