Evidence map›Paper›PMID 37702553›Full record

ArticleJournal of magnetic resonance imaging : JMRI2024

MR Neurography and Quantitative Muscle MRI of Parsonage Turner Syndrome Involving the Long Thoracic Nerve.

Jonathan Morena, Ek T Tan, Gracyn J Campbell, Pravjit Bhatti, Qian Li, Christian S Geannette, Yenpo Lin, Carlo J Milani, Darryl B Sneag

Open access · greenAbstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Jonathan MorenaDepartment of Neurology, Hospital for Special Surgery, New York City, New York, USA.ORCID 0000-0002-2952-0064
Ek T TanDepartment of Radiology and Imaging, Hospital for Special Surgery, New York City, New York, USA.ORCID 0000-0003-2847-9378
Gracyn J CampbellDepartment of Radiology and Imaging, Hospital for Special Surgery, New York City, New York, USA.ORCID 0009-0004-9794-3685
Pravjit BhattiGeorgetown University School of Medicine, Washington, D.C., USA.ORCID 0000-0003-2968-0364
Qian LiDepartment of Biostatistics, Hospital for Special Surgery, New York City, New York, USA.
Christian S GeannetteDepartment of Radiology and Imaging, Hospital for Special Surgery, New York City, New York, USA.
Yenpo LinDepartment of Radiology and Imaging, Hospital for Special Surgery, New York City, New York, USA.
Carlo J MilaniDepartment of Physiatry, Hospital for Special Surgery, New York City, New York, USA.
Darryl B SneagDepartment of Radiology and Imaging, Hospital for Special Surgery, New York City, New York, USA.ORCID 0000-0002-9105-5415
Hospital for Special Surgery · USGeorgetown University · US

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Magnetic resonance and ultrasound imaging as biomarkers for detection and monitoring of Parsonage-Turner Syndrome (PTS)R21TR003033 · NCATS · HOSPITAL FOR SPECIAL SURGERY · PI SNEAG, DARRYL · 2020 to 2021
$352k
NCATS NIH HHS R21 TR003033NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002384
6 · The paper itself

Abstract

backgroundParsonage-Turner syndrome (PTS) is characterized by severe, acute upper extremity pain and subsequent paresis and most commonly involves the long thoracic nerve (LTN). While MR neurography (MRN) can detect LTN hourglass-like constrictions (HGCs), quantitative muscle MRI (qMRI) can quantify serratus anterior muscle (SAM) neurogenic changes. PURPOSE/HYPOTHESIS: 1) To characterize qMRI findings in LTN-involved PTS. 2) To investigate associations between qMRI and clinical assessments of HGCs/electromyography (EMG). STUDY TYPE: Prospective. POPULATION: 30 PTS subjects (25 M/5 F, mean/range age = 39/15-67 years) with LTN involvement who underwent bilateral chest wall qMRI and unilateral brachial plexus MRN. FIELD STRENGTH/SEQUENCES: 3.0 Tesla/multiecho spin-echo T2-mapping, diffusion-weighted echo-planar-imaging, multiecho gradient echo. ASSESSMENT: qMRI was performed to obtain T2, muscle diameter fat fraction (FF), and cross-sectional area of the SAM. Clinical reports of MRN and EMG were obtained; from MRN, the number of HGCs; from EMG, SAM measurements of motor unit recruitment levels, fibrillations, and positive sharp waves. qMRI/MRN were performed within 90 days of EMG. EMG was performed on average 185 days from symptom onset (all ≥2 weeks from symptom onset) and 5 days preceding MRI. STATISTICAL TESTS: Paired t-tests were used to compare qMRI measures in the affected SAM versus the contralateral, unaffected side (P < 0.05 deemed statistically significant). Kendall's tau was used to determine associations between qMRI against HGCs and EMG.

resultsRelative to the unaffected SAM, the affected SAM had increased T2 (50.42 ± 6.62 vs. 39.09 ± 4.23 msec) and FF (8.45 ± 9.69 vs. 4.03% ± 1.97%), and decreased muscle diameter (74.26 ± 21.54 vs. 88.73 ± 17.61 μm) and cross-sectional area (9.21 ± 3.75 vs. 16.77 ± 6.40 mm DATA

conclusionqMRI changes in the SAM were observed in subjects with PTS involving the LTN. LEVEL OF EVIDENCE: 2 TECHNICAL EFFICACY: Stage 1.

Indexed as

Magnetic Resonance ImagingMuscle, SkeletalThoracic NervesAdolescentAdultAgedBrachial PlexusBrachial Plexus NeuritisElectromyographyFemaleHumansMaleMiddle AgedProspective StudiesYoung Adultlong thoracic nerveMR neurographyParsonage‐Turner syndromequantitative MRIscapular winging

Identifiers

PMID37702553
PMCPMC10932860
OpenAlexW4386704571

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.