Evidence map›Paper›PMID 37702495›Full record

ArticleJournal of clinical microbiology2023

Evaluation of the QIAstat-Dx Meningitis/Encephalitis Panel, a multiplex PCR platform for the detection of community-acquired meningoencephalitis.

Thomas Sundelin, Johanna Bialas, Juana de Diego, Markus Hermanowski, Hendrik Leibhan, Léa Ponderand, Marti Juanola-Falgarona, Tara Jones, Melisa Rey, Sarah Johnson and 2 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Journal of clinical microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Review
  5. Review
  6. Article
  7. New microbes and new infections · 2025
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. A multicenter evaluation of the QIAstat-Dx meningitis-encephalitis syndromic test kit as compared to the conventional diagnostic microbiology workflow.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  20. Stewardship of Molecular Diagnostics in Transplant Viral Infections.Transplant infectious disease : an official journal of the Transplantation Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 4 countries.

Thomas Sundelin *Department of Clinical Microbiology, Herlev and Gentofte Hospital , Herlev, Denmark.
Johanna Bialas *Labor Berlin-Charite Vivantes Services GmbH , Berlin, Germany.
Juana de DiegoLabor Berlin-Charite Vivantes Services GmbH , Berlin, Germany.
Markus HermanowskiLabor Berlin-Charite Vivantes Services GmbH , Berlin, Germany.
Hendrik LeibhanLabor Berlin-Charite Vivantes Services GmbH , Berlin, Germany.
Léa PonderandLaboratoire de bactériologie, CHU Grenoble Alpes , La Tronche, France.
Marti Juanola-FalgaronaSTAT-Dx Life S.L. (a QIAGEN Company), Carrer de Baldiri Reixac , Barcelona, Spain.ORCID 0000-0002-4566-7154
Tara JonesQIAGEN Ltd , Manchester, United Kingdom.
Melisa ReySTAT-Dx Life S.L. (a QIAGEN Company), Carrer de Baldiri Reixac , Barcelona, Spain.ORCID 0000-0001-9433-2222
Sarah JohnsonQIAGEN Ltd , Manchester, United Kingdom.
Josep ParejaSTAT-Dx Life S.L. (a QIAGEN Company), Carrer de Baldiri Reixac , Barcelona, Spain.
Yvan Caspar *Laboratoire de bactériologie, CHU Grenoble Alpes , La Tronche, France.
Vivantes Klinikum · DECentre National de la Recherche Scientifique · FRQiagen (United Kingdom) · GBGentofte Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid identification of the causative pathogens of central nervous system infections is essential for providing appropriate management and improving patient outcomes. The performance of QIAstat-Dx Meningitis/Encephalitis (ME) Panel-a multiplex PCR testing platform-in detecting pathogens implicated in meningitis and/or encephalitis was evaluated using BioFire FilmArray ME Panel as a comparator method. This multicenter study analyzed 585 retrospective residual cerebrospinal fluid specimens and 367 contrived specimens. The QIAstat-Dx ME Panel showed positive percent agreement (PPA) values of 100% for

Indexed as

EncephalitisMeningitisMeningoencephalitisHumansMultiplex Polymerase Chain ReactionRetrospective Studiesencephalitismeningitismolecular diagnosticsmultiplexQIAstat-Dxreal-time PCR

Identifiers

PMID37702495
PMCPMC10595057
OpenAlexW4386705223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.