Evidence map›Paper›PMID 37702393›Full record

ArticleRNA biology2023

Translational control of murine adiponectin expression by an upstream open reading frame element.

Kommireddy Vasu, Iyappan Ramachandiran, Aayushi Chechi, Krishnendu Khan, Debjit Khan, Randall Kaufman, Paul L Fox

Open access · goldAbstract read
In one paragraph

Article in RNA biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kommireddy VasuDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
Iyappan RamachandiranDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
Aayushi ChechiDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
Krishnendu KhanDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
Debjit KhanDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
Randall KaufmanDegenerative Diseases Program, Center for Genetic Disorders and Aging Research, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Paul L FoxDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
Cleveland Clinic · USSanford Burnham Prebys Medical Discovery Institute · US

Funding

ER stress and UPR in non-alcoholic steatohepatitis and hepatocellular carcinomaR01CA198103 · NCI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI KAUFMAN, RANDAL J. · 2016 to 2020
$3.4M
The National Diabetes Prevention Program in Rural CommunitiesR01DK132362 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Anna Michael Gorczyca · 2023 to 2026
$2.6M
Childhood-onset hypomyelinating leukodystrophy and the multi-tRNA synthetase complexR01NS124581 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI Ranjan Dutta, PAUL L FOX · 2023 to 2026
$2.5M
Mechanism of ER Protein Misfolding-Induced Mitochondrial DysfunctionR01DK113171 · NIDDK · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI KAUFMAN, RANDAL J. · 2017 to 2020
$2.5M
Adipokines, Aging, and Alzheimers DiseaseR01AG067146 · NIA · CLEVELAND CLINIC LERNER COM-CWRU · PI FOX, PAUL L · 2020 to 2024
$2.4M
The mammalian multi-tRNA synthetase complexR01NS124547 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI PAUL L FOX, Valentin Gogonea · 2022 to 2026
$2.4M
Assay Development for Discovery of a Small Molecule Inhibitor of a Novel Metabolic Pathway that Drives ObesityR01DK124203 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI FOX, PAUL L · 2020 to 2022
$1.2M
American Heart Association-American Stroke Association 19POST34380725NCI NIH HHS R01 CA198103NIA NIH HHS R01 AG067146NIDDK NIH HHS R01 DK113171NIDDK NIH HHS R01 DK124203NIDDK NIH HHS R01 DK132362NINDS NIH HHS R01 NS124547NINDS NIH HHS R01 NS124581
6 · The paper itself

Abstract

Adiponectin, an adipocyte-specific secretory protein encoded by the

Indexed as

AdipocytesAdiponectin3T3-L1 CellsAnimalsBiological TransportMammalsMiceOpen Reading FramesAdiponectinadipocyteadiponectinAdipoqCRISPR-Cas9eukaryotic initiation factor 2alphaintegrated stress responsetranslationUpstream open reading frame

Identifiers

PMID37702393
PMCPMC10501164
OpenAlexW4386703765

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.