Evidence map›Paper›PMID 37702048›Full record

ReviewCirculation. Cardiovascular quality and outcomes2023

Global Cardio Oncology Registry (G-COR): Registry Design, Primary Objectives, and Future Perspectives of a Multicenter Global Initiative.

Arco J Teske, Rohit Moudgil, Teresa López-Fernández, Ana Barac, Sherry Ann Brown, Anita Deswal, Tomas G Neilan, Sarju Ganatra, Husam Abdel Qadir, Venu Menon and 24 more

Open access · greenAbstract readReview
In one paragraph

Review in Circulation. Cardiovascular quality and outcomes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. The Current Cardio-Oncology Landscape Across Australia.Current treatment options in oncology · 2026
    Review
  3. Article
  4. Research Priorities and Future Directions in Cardio-Oncology.Current treatment options in oncology · 2026
    Review
  5. Integrated Cardio-oncology Service.Cardiac failure review · 2026
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Cardio-oncology: chances and challenges.Basic research in cardiology · 2025
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

34 authors at 20 institutions in 12 countries.

Arco J TeskeDepartment of Cardiology, University Medical Centre Utrecht, The Netherlands (A.J.T.).ORCID 0000-0001-5305-1619
Rohit MoudgilDepartment of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic Foundation, OH (R.M., V.M., P.C.).ORCID 0000-0001-8258-0675
Teresa López-FernándezHospital Universitario La Paz, Madrid, Spain (T.L.-F.).ORCID 0000-0002-3414-7022
Ana BaracMedstar Heart Institute, Georgetown University, WA, DC (A.B.).ORCID 0000-0002-9935-8904
Sherry Ann BrownMedical College of Wisconsin, Milwaukee (S.A.B.).
Anita DeswalMD Anderson Cancer Center, Houston, TX (A.D.).ORCID 0000-0002-6147-9591
Tomas G NeilanMassachusetts General Hospital, Harvard Medical School, Boston (T.G.N.).ORCID 0000-0002-1513-8833
Sarju GanatraLahey Hospital and Medical Center, Beth Israel Lahey Health, Burlington, MA (S.G.).
Husam Abdel QadirUniversity of Toronto, Canada (H.A.Q.).
Venu MenonDepartment of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic Foundation, OH (R.M., V.M., P.C.).ORCID 0000-0003-4410-2677
Aaron L SverdlovNewcastle Centre of Excellence in Cardio-Oncology, Calvary Mater Newcastle, Hunter Medical Research Institute, John Hunter Hospital, University of Newcastle, NSW, Australia (A.L.S.).ORCID 0000-0003-2539-8038
Richard K ChengUniversity of Washington Medical Center, Seattle (R.K.C.).ORCID 0000-0001-5994-5998
Silvia MakhoulHospital Juan A Fernández/Hospital Británico de Buenos Aires Buenos Aires, Argentina (S.M.).ORCID 0000-0002-2455-8434
Arjun K GhoshBarts Heart Centre, St Bartholomew's Hospital (A.K.G.), London, United Kingdom.ORCID 0000-0003-4992-2412
Sebastian SzmitCentre of Postgraduate Medical Education, Warsaw, Poland (S.S.).ORCID 0000-0002-3075-1943
Vlad ZahaUT Southwestern Medical Center, Dallas, TX (V.Z.).ORCID 0000-0003-4878-891X
Daniel AddisonOhio State University, Columbus (D.A.).ORCID 0000-0002-9113-8333
Lili ZhangMontefiore Medical Center/Albert Einstein College of Medicine, NY (L.Z.).
Joerg HerrmannMayo Clinic, Rochester, MN (J.H.).
Jun H ChongNational Heart Centre, Singapore (J.H.C.).
Vivek AgarwalaNarayana Superspeciality Hospital and Cancer Institute and RN Tagore Cancer Center, Kolkata, India (V.A.).ORCID 0000-0003-1381-0320
Zaza IakobishviliDepartment of Cardiology, Tel Aviv Jaffa District Clalit Health Services, Tel Aviv, Israel (Z.I.).ORCID 0000-0002-3324-4883
Patricia GuerreroAdventHealth, Orlando, FL (P.G.).
Eric H YangUniversity of California Los Angeles (E.H.Y.).ORCID 0000-0003-4889-7454
Monika LejaUniversity of Michigan Medical Center, Ann Arbor (M.L.).
Nausheen AkhterNorthwestern University Feinberg School of Medicine, Chicago, IL (N.A.).ORCID 0000-0001-9423-8578
Avirup GuhaCardio-Oncology Program, Department of Medicine, Georgia Cancer Center, Medical College of Georgia at Augusta University, GA (A.G.).ORCID 0000-0003-0253-1174
Tochukwu M OkwuosaRush University Medical Center, Chicago, IL (T.M.O.).ORCID 0000-0001-7666-1217
Carolina Carvalho SilvaRede D'Or Hospital Group, Sao Paulo, Brazil (C.C.S.).
Patrick CollierDepartment of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic Foundation, OH (R.M., V.M., P.C.).ORCID 0000-0003-3941-9653
Jeanne DeCaraUniversity of Chicago School of Medicine, IL (J.D.C.).ORCID 0000-0002-8234-3132
Brenton BauerCOR Healthcare Associates/Torrance Memorial Medical Center, CA (B.B.).ORCID 0009-0002-5804-8907
Carrie E LennemanUniversity of Alabama at Birmingham (C.E.L.).
Diego SadlerCleveland Clinic Florida, Weston (D.S.).ORCID 0000-0001-6268-4127
Cleveland Clinic · USAdventHealth Orlando · USAlbert Einstein College of Medicine · USAugusta University · USCancer Hospital and Research Institute · INClalit Health Services · ILCleveland Clinic Florida · USD’Or Institute for Research and Education · BRGeorgetown University · USHospital Fernández · ARHospital Universitario La Paz · ESJohn Hunter Hospital · AULahey Medical Center · USMassachusetts General Hospital · USMayo Clinic · USMedical College of Wisconsin · USNational Heart Centre Singapore · SGNorthwestern University · USPostgraduate School of Molecular Medicine · PLRush University Medical Center · US

Funding

TrAstuzumab Cardiomyopathy Therapeutic Intervention with Carvedilol (TACTIC) TrialR01CA233610 · NCI · MAYO CLINIC ROCHESTER · PI HERRMANN, JOERG, RUDDY, KATHRYN JEAN · 2019 to 2024
$4.3M
CTSA K12 Program at Einstein-MontefioreK12TR004411 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Deepa Rastogi · 2023 to 2026
$3.0M
NCATS NIH HHS K12 TR004411NCI NIH HHS R01 CA233610
6 · The paper itself

Abstract

backgroundGlobal collaboration in cardio-oncology is needed to understand the prevalence of cancer therapy-related cardiovascular toxicity in different risk groups, practice settings, and geographic locations. There are limited data on the socioeconomic and racial/ethnic disparities that may impact access to care and outcomes. To address these gaps, we established the Global Cardio-Oncology Registry, a multinational, multicenter prospective registry.

methodsWe assembled cardiologists and oncologists from academic and community settings to collaborate in the first Global Cardio-Oncology Registry. Subsequently, a survey for site resources, demographics, and intention to participate was conducted. We designed an online data platform to facilitate this global initiative.

resultsA total of 119 sites responded to an online questionnaire on their practices and main goals of the registry: 49 US sites from 23 states and 70 international sites from 5 continents indicated a willingness to participate in the Global Cardio-Oncology Registry. Sites were more commonly led by cardiologists (85/119; 72%) and were more often university/teaching (81/119; 68%) than community based (38/119; 32%). The average number of cardio-oncology patients treated per month was 80 per site. The top 3 Global Cardio-Oncology Registry priorities in cardio-oncology care were breast cancer, hematologic malignancies, and patients treated with immune checkpoint inhibitors. Executive and scientific committees and specific committees were established. A pilot phase for breast cancer using Research Electronic Data Capture Cloud platform recently started patient enrollment.

conclusionsWe present the structure for a global collaboration. Information derived from the Global Cardio-Oncology Registry will help understand the risk factors impacting cancer therapy-related cardiovascular toxicity in different geographic locations and therefore contribute to reduce access gaps in cardio-oncology care. Risk calculators will be prospectively derived and validated.

Indexed as

Breast NeoplasmsCardiologistsCardiologyNeoplasmsFemaleHumansMedical OncologyMulticenter Studies as TopicRegistriescardiologycardiotoxicitycardiovascular diseasehematologymyocarditis

Identifiers

PMID37702048
PMCPMC10824596
OpenAlexW4386704671

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.