Evidence map›Paper›PMID 37701982›Full record

ArticlePediatric pulmonology2023

Peripheral airway dysfunction in prematurity-associated obstructive lung disease identified by oscillometry.

Michael Cousins, Kylie Hart, Bence L Radics, A John Henderson, Zoltán Hantos, Peter D Sly, Sailesh Kotecha

Open access · hybridAbstract read
In one paragraph

Article in Pediatric pulmonology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Lung volumes, gas transfer and oscillometry after preterm birth: systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Michael CousinsDepartment of Child Health, Cardiff University School of Medicine, Cardiff, UK.
Kylie HartDepartment of Child Health, Cardiff University School of Medicine, Cardiff, UK.
Bence L RadicsDepartment of Pathology, University of Szeged, Szeged, Hungary.
A John HendersonMRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Zoltán HantosDepartment of Anesthesiology and Intensive Therapy, Semmelweis University, Budapest, Hungary.
Peter D SlyChild Health Research Center, The University of Queensland, South Brisbane, Australia.ORCID 0000-0001-6305-2201
Sailesh KotechaDepartment of Child Health, Cardiff University School of Medicine, Cardiff, UK.ORCID 0000-0003-3535-7627
Cardiff and Vale University Health Board · GBCardiff University · GBSemmelweis University · HUThe University of Queensland · AUUniversity of Bristol · GBUniversity of Szeged · HU

Funding

Medical Research Council MR/M022552/1
6 · The paper itself

Abstract

introductionMechanisms underlying lung dysfunction after preterm birth are poorly understood. Studying phenotypes of prematurity-associated lung disease may aid understanding of underlying mechanisms. Preterm-born children with and without lung dysfunction and term controls were assessed using oscillometry before and after exercise, and after postexercise bronchodilation.

methodsPreterm-born children, born at gestation of 34 weeks or less, were classified into those with prematurity-associated obstructive lung disease (POLD; FEV

resultsFrom 241 participants aged 7-12 years, complete data were available from 179: 15 children with POLD and 11 with pPRISm were compared with 93 preterm and 60 term controls. POLD group, when compared to both control groups, had impaired impedance, greater resistance, more negative (greater magnitude) reactance at low frequencies, and also had decreased compliance. pPRISm group demonstrated impaired reactance and compliance compared to term controls. No differences were noted between the preterm and term controls. Exercise had little impact on oscillometry values, but children with POLD had greatest improvements after postexercise bronchodilator administration, with decreased resistance and decreased magnitude of reactance, particularly at low frequencies.

conclusionPreterm-born children with obstructive airway disease had the greatest oscillometry impairments and the largest improvements after postexercise bronchodilator compared to control groups. Oscillometry can potentially be used to identify preterm-born children with lung disease to institute treatment.

Indexed as

Infant, Newborn, DiseasesLung DiseasesLung Diseases, ObstructivePremature BirthBronchodilator AgentsChildFemaleForced Expiratory VolumeHumansInfant, NewbornLungOscillometrySpirometryBronchodilator Agentsairway obstructionalbuteroloscillometrypremature birthrespiratory mechanics

Identifiers

PMID37701982
PMCPMC10947003
OpenAlexW4386695305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.