ReviewFrontiers in molecular neuroscience2023
Zebrafish as a robust preclinical platform for screening plant-derived drugs with anticonvulsant properties-a review.
Review in Frontiers in molecular neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Lithium pretreatment does not affect pilocarpine-induced seizure-like activity in zebrafish larvae.Pharmacological reports : PR · 2026Article
- Recent Advance in the Sample Pretreatments for Drug Analysis in Zebrafish.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Potential Effect of Belladonna in the Management of Convulsions in Zebrafish (Annals of neurosciences · 2026Article
- Zebrafish as a multimodal platforms for anti-inflammatory phytomedicine discovery and translation.Frontiers in pharmacology · 2026Review
- Design and Development of Sulfonamide-Chalcones as Antiepileptic Candidates: Computational and Zebrafish-Based Validation Approaches.ACS omega · 2025Article
- A selective small-molecule agonist of G protein-gated inwardly-rectifying potassium channels reduces epileptiform activity in mouse models of tumor-associated and provoked seizures.Neuropharmacology · 2025Article
- Effects of two different peptides on pentylenetetrazole-induced seizures in larval zebrafish.PloS one · 2025Article
- In silico investigation of potential phytoconstituents against ligand- and voltage-gated ion channels as antiepileptic agents.3 Biotech · 2024Article
- A review of MPTP-induced parkinsonism in adult zebrafish to explore pharmacological interventions for human Parkinson's disease.Frontiers in neuroscience · 2024Review
- Induction of seizures and initiation of epileptogenesis by pilocarpine in zebrafish larvae.Frontiers in molecular neuroscience · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traditionally, selected plant sources have been explored for medicines to treat convulsions. This continues today, especially in countries with low-income rates and poor medical systems. However, in the low-income countries, plant extracts and isolated drugs are in high demand due to their good safety profiles. Preclinical studies on animal models of seizures/epilepsy have revealed the anticonvulsant and/or antiepileptogenic properties of, at least some, herb preparations or plant metabolites. Still, there is a significant number of plants known in traditional medicine that exert anticonvulsant activity but have not been evaluated on animal models. Zebrafish is recognized as a suitable
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.