Evidence map›Paper›PMID 37701826›Full record

ArticlePeerJ2023

Dieting alleviates hyperuricemia and organ injuries in uricase-deficient rats

Yun Yu, Xulian Wan, Dan Li, Yalin Qi, Ning Li, Guangyun Luo, Hua Yin, Lei Wang, Wan Qin, Yongkun Li and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yun Yu *School of Basic Medicine, Kunming Medical University, Kunming, Yunnan, China.
Xulian Wan *School of Chinese Medicine, Yunnan University of Traditional Chinese Medicne, Kunming, Yunnan, China.
Dan LiSchool of Basic Medicine, Kunming Medical University, Kunming, Yunnan, China.
Yalin QiSchool of Basic Medicine, Yunnan University of Traditional Chinese Medicine, Kunming, Yunnan, China.
Ning LiSchool of Basic Medicine, Yunnan University of Traditional Chinese Medicine, Kunming, Yunnan, China.
Guangyun LuoSchool of Basic Medicine, Yunnan University of Traditional Chinese Medicine, Kunming, Yunnan, China.
Hua YinSchool of Basic Medicine, Yunnan University of Traditional Chinese Medicine, Kunming, Yunnan, China.
Lei WangSchool of Basic Medicine, Kunming Medical University, Kunming, Yunnan, China.
Wan QinSchool of Chinese Medicine, Yunnan University of Traditional Chinese Medicne, Kunming, Yunnan, China.
Yongkun LiSchool of Chinese Medicine, Yunnan University of Traditional Chinese Medicne, Kunming, Yunnan, China.
Lvyu LiThe Third Affiliated Hospital, Yunnan University of Traditional Chinese Medicine, Kunming, Yunnan, China.
Weigang DuanSchool of Basic Medicine, Yunnan University of Traditional Chinese Medicine, Kunming, Yunnan, China.
Yunnan University of Traditional Chinese Medicine · CNKunming Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dieting is a basic treatment for lowering hyperuricemia. Here, we aimed to determine the optimal amount of dietary food that lowers serum uric acid (SUA) without modifying the dietary ingredients in rats. Increased SUA was found in food-deprived 45-day-old uricase-deficient rats (Kunming-DY rats), and the optimal amount of dietary food (75% dietary intake) to lower SUA was established by controlling the amount of food given daily from 25% to 100% for 2 weeks. In addition to lowering SUA by approximately 22.5 ± 20.5%, the optimal amount of dietary food given for 2 weeks inhibited urine uric acid excretion, lowered the uric acid content in multiple organs, improved renal function, lowered serum triglyceride, alleviated organ injuries (

Indexed as

HyperuricemiaAnimalsCell CycleCell DivisionPharmaceutical VehiclesRatsUrate OxidaseUric AcidPharmaceutical VehiclesUrate OxidaseUric AcidCell cycle pathwayDietingFastingHyperuricemiaRenal injurySerum uric acidUricase-deficient rats

Identifiers

PMID37701826
PMCPMC10494837
OpenAlexW4386564070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.