Evidence map›Paper›PMID 37701672›Full record

ArticleOpen veterinary journal2023

Evaluation of renal disturbance in animal models of polycystic ovary syndrome.

Yudit Oktanella, Handayu Untari, Dyah Kinasih Wuragil, Hana Ismiawati, Nur Afidatul Hasanah, Galuh Chandra Agustina, Dyah Ayu Oktavianie Pratama

Open access · goldAbstract read
In one paragraph

Article in Open veterinary journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yudit OktanellaFaculty of Veterinary Medicine, Brawijaya University, Malang, Indonesia.
Handayu UntariFaculty of Veterinary Medicine, Brawijaya University, Malang, Indonesia.
Dyah Kinasih WuragilFaculty of Veterinary Medicine, Brawijaya University, Malang, Indonesia.
Hana IsmiawatiFaculty of Veterinary Medicine, Brawijaya University, Malang, Indonesia.
Nur Afidatul HasanahFaculty of Veterinary Medicine, Brawijaya University, Malang, Indonesia.
Galuh Chandra AgustinaFaculty of Veterinary Medicine, Brawijaya University, Malang, Indonesia.
Dyah Ayu Oktavianie PratamaFaculty of Veterinary Medicine, Brawijaya University, Malang, Indonesia.
University of Brawijaya · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Polycystic ovary syndrome (PCOS) is an endocrine disease characterized by hyperandrogenism and hyperinsulinemia, followed by luteinizing hormone and follicle-stimulating hormone deficiency. PCOS conditions cause metabolic disorders that increase uric acid levels and malondialdehyde (MDA) levels. Animal models of PCOS have been used extensively in research to study the pathogenesis, clinical characteristics, and treatment of PCOS. Aim: This study aimed to identify the pathological mechanisms underlying renal dysfunction in PCOS by observing several parameters, including blood urea nitrogen (BUN), creatinine, uric acid, and renal MDA levels. Methods: This research was an experimentally designed study using a Wistar rat ( Results: According to statistical analysis it indicated that induction of TP and EV can increase blood uric acid levels in PCOS model rats ( Conclusion: Based on the results of this study, it can be concluded that the induction of animal models with TP can trigger significant renal damage compared to EV.

Indexed as

Polycystic Ovary SyndromeAnimalsCreatinineFemaleKidneyModels, AnimalRatsRats, WistarUric AcidCreatinineUric AcidAnimal modelEstradiol valeratePCOSRenal disturbanceTestosterone propionate

Identifiers

PMID37701672
PMCPMC10495098
OpenAlexW4386363363

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.