Evidence map›Paper›PMID 37701578›Full record

ArticleiScience2023

Active shrinkage protects neurons following axonal transection.

Mehmet Şerif Aydın, Sadık Bay, Esra Nur Yiğit, Cemil Özgül, Elif Kaval Oğuz, Elçin Yenidünya Konuk, Neşe Ayşit, Nureddin Cengiz, Ender Erdoğan, Aydın Him and 3 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. D-Fructose Exposure Impairs Neuronal Development in Mouse Neural Stem Cells.International journal of molecular sciences · 2026
    Article
  4. A Novel Method for Culturing Telencephalic Neurons in Axolotls.The Journal of comparative neurology · 2025
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Mehmet Şerif AydınRegenerative and Restorative Medicine Research Center (REMER), Research Institute for Health Sciences and Technologies (SABITA), Istanbul Medipol University, Istanbul 34810, Türkiye.
Sadık BayRegenerative and Restorative Medicine Research Center (REMER), Research Institute for Health Sciences and Technologies (SABITA), Istanbul Medipol University, Istanbul 34810, Türkiye.
Esra Nur YiğitRegenerative and Restorative Medicine Research Center (REMER), Research Institute for Health Sciences and Technologies (SABITA), Istanbul Medipol University, Istanbul 34810, Türkiye.
Cemil ÖzgülRegenerative and Restorative Medicine Research Center (REMER), Research Institute for Health Sciences and Technologies (SABITA), Istanbul Medipol University, Istanbul 34810, Türkiye.
Elif Kaval OğuzDepartment of Science Education, Faculty of Education, Yüzüncü Yıl University, Van 65080, Türkiye.
Elçin Yenidünya KonukDepartment of Medical Biology, School of Medicine, Bakırçay University, İzmir 35665, Türkiye.
Neşe AyşitRegenerative and Restorative Medicine Research Center (REMER), Research Institute for Health Sciences and Technologies (SABITA), Istanbul Medipol University, Istanbul 34810, Türkiye.
Nureddin CengizDepartment of Histology and Embryology, School of Medicine, Bandırma Onyedi Eylül University, Bandırma, Balıkesir 10200, Türkiye.
Ender ErdoğanDepartment of Histology and Embryology, School of Medicine, Selçuk University, Konya 42130, Türkiye.
Aydın HimDepartment of Physiology, School of Medicine, Bolu Abant İzzet Baysal University, Bolu 14030, Türkiye.
Mehmet KoçakBiostatistics and Bioinformatics Analysis Unit, Research Institute for Health Sciences and Technologies (SABITA), Istanbul Medipol University, Istanbul 34810, Türkiye.
Emrah ErogluRegenerative and Restorative Medicine Research Center (REMER), Research Institute for Health Sciences and Technologies (SABITA), Istanbul Medipol University, Istanbul 34810, Türkiye.
Gürkan ÖztürkRegenerative and Restorative Medicine Research Center (REMER), Research Institute for Health Sciences and Technologies (SABITA), Istanbul Medipol University, Istanbul 34810, Türkiye.
Istanbul Medipol University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trauma, vascular events, or neurodegenerative processes can lead to axonal injury and eventual transection (axotomy). Neurons can survive axotomy, yet the underlying mechanisms are not fully understood. Excessive water entry into injured neurons poses a particular risk due to swelling and subsequent death. Using

Indexed as

Biological sciencesNeurosciencePhysiology

Identifiers

PMID37701578
PMCPMC10493506
OpenAlexW4386170813

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.