Evidence map›Paper›PMID 37701535›Full record

ArticleTherapeutic advances in urology

Does unenhanced computerized tomography as imaging standard post-retrograde intrarenal surgery paradoxically reduce stone-free rate and increase additional treatment for residual fragments? Outcomes from 5395 patients in the FLEXOR study by the TOWER group.

Vineet Gauhar, Daniele Castellani, Ben Hall Chew, Daron Smith, Chu Ann Chai, Khi Yung Fong, Jeremy Yuen-Chun Teoh, Olivier Traxer, Bhaskar Kumar Somani, Thomas Tailly

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 8 countries.

Vineet GauharDepartment of Urology, Ng Teng Fong General Hospital, Singapore, Singapore.
Daniele CastellaniUrology Unit, Azienda Ospedaliero-Universitaria delle Marche, Università Politecnica delle Marche, Via Conca 71, Ancona 60126, Italy.ORCID https://orcid.org/0000-0001-7354-9190
Ben Hall ChewDepartment of Urology, University of British Columbia, Vancouver, BC, Canada.
Daron SmithInstitute of Urology, University College Hospital London, London, UK.
Chu Ann ChaiUrology Unit, Department of Surgery, University of Malaya, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0001-8915-3617
Khi Yung FongYong Loo Lin School of Medicine, National University of Singapore, Singapore.
Jeremy Yuen-Chun TeohS.H. Ho Urology Centre, Department of Surgery, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Olivier TraxerDepartment of Urology AP-HP, Sorbonne University, Tenon Hospital, Paris, France.
Bhaskar Kumar SomaniDepartment of Urology, University Hospitals Southampton, NHS Trust, Southampton, UK.ORCID https://orcid.org/0000-0002-6248-6478
Thomas TaillyDepartment of Urology, University Hospital of Ghent, Ghent, Belgium.
Chinese University of Hong Kong · HKGhent University Hospital · BEMarche Polytechnic University · ITNational University of Singapore · SGNg Teng Fong General Hospital · SGSorbonne Université · FRUniversity College Hospital · GBUniversity of British Columbia · CAUniversity of Malaya · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Assessment of residual fragments (RFs) is a key step after treatment of kidney stones. Objective: To evaluate differences in RFs estimation based on unenhanced computerized tomography (CT) Design: A retrospective analysis of data from 20 centers of adult patients who had RIRS was done (January 2018-August 2021). Methods: Exclusion criteria: ureteric stones, anomalous kidneys, bilateral renal stones. Patients were divided into two groups (group 1: CT; group 2: plain X-rays or combination of X-rays/ultrasound within 3 months after RIRS). Clinically significant RFs (CSRFs) were considered RFs ⩾ 4 mm. One-to-one propensity score matching for age, gender, and stone characteristics was performed. Multivariable logistic regression analysis was performed to evaluate independent predictors of CSRFs. Results: A total of 5395 patients were included (1748 in group 1; 3647 in group 2). After matching, 608 patients from each group with comparable baseline and stone characteristics were included. CSRFs were diagnosed in 1132 patients in the overall cohort (21.0%). Post-operative CT reported a significantly higher number of patients with RFs ⩾ 4 mm, before (35.7% Conclusions: CT is the only reliable imaging to assess the burden of RFs following RIRS and urologist should consider at least one CT scan to determine the same and definitely plan reintervention only based on CT rather than ultrasound and X-ray combination.

Indexed as

computerized tomographyflexible ureteroscopykidney calculilaserlithotripsyradiographyretrograde intrarenal surgeryultrasonography

Identifiers

PMID37701535
PMCPMC10493056
OpenAlexW4386576323

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.