ArticleLancet regional health. Americas2023
Prevalence of depressive disorder in the adult population of Latin America: a systematic review and meta-analysis.
Article in Lancet regional health. Americas, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 31 citations in OpenAlex.
- Digital positive affect intervention (PAI) versus self-monitoring placebo in the treatment of anxiety and depression: a two-arm randomized controlled trial (RCT).BMC psychiatry · 2025Trial
- Community violence exposure and mental health in urban Mexico: The moderating role of school belonging in early adolescence and young adulthood.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2026Article
- Female sex: beyond risk prediction in mental health.Lancet regional health. Americas · 2026Article
- Association of the C-1019G (rs6295) Polymorphism of theDiseases (Basel, Switzerland) · 2026Article
- Social network structure and depression by gender in rural Honduras: a cross-sectional study.BMJ open · 2026Observational
- Racial Inequality in the Prevalence of Symptom-Based Depression Versus Self-Reported Medical Diagnosis in Brazil.Journal of racial and ethnic health disparities · 2026Article
- Functional Genomics Studies of Psychiatric Disorders in Individuals of Latin American Populations: A Scoping Review.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2026Article
- Article
- Sociodemographic factors associated with depressive symptoms and self-care agency capacity in hypertensive older adults from Loja, Ecuador: a cross-sectional study.Frontiers in public health · 2026Article
- Evaluation of GABA-Producing Fermented Whey Formulations: From Strain Selection to Raspberry-Enriched Beverages with Psychobiotic Potential.Foods (Basel, Switzerland) · 2025Article
- Human development, inequality, and their associations with brain structure across 29 countries.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- The C/C Genotype of the C-1019G (rs6295) Polymorphism of the 5-HT1A Receptor Gene Is Associated with Lower Susceptibility to Depressive Symptoms in a Rural Population in Mexico.Neurology international · 2025Article
- Psychiatric genetics in the diverse landscape of Latin American populations.Nature genetics · 2025Review
- Prevalence of anxiety disorders in Latin America: a systematic review and meta-analysis.Lancet regional health. Americas · 2025Article
- Clustering the Depression Prevalence in Indonesia Provinces through Natural Breaks Jenks Method.Clinical practice and epidemiology in mental health : CP & EMH · 2025Article
- Cheers to anxiety: Granger causality insights on alcohol consumption patterns across 13 South American countries.BMC public health · 2024Article
- Mental disorders in adults from Ribeirão Preto, Brazil: a cross-sectional analysis of two birth cohorts.BMC public health · 2024Article
- Article
- A contextual understanding of the high prevalence of depression in Latin America.Lancet regional health. Americas · 2024Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Depressive disorder is one of the leading causes of disability worldwide; however its prevalence and association with inequality and crime is poorly characterised in Latin America. This study aimed to: Methods: We conducted a systematic review and meta-analysis of population-based studies reporting primary data on the prevalence of ICD/DSM depressive disorder in Latin America from 1990 to 2023, irrespective of language. We searched PubMed, PsycINFO, Cochrane Library, SciELO (regional database), LILAC (regional database), and available grey literature. Study quality was assessed using JBI's critical appraisal tools. We generated pooled estimates using random-effects meta-analysis; heterogeneity was assessed using the Findings: Using data from 40 studies in Latin America, lifetime, 12-month, and current prevalence of ICD/DSM depressive disorder were calculated at 12.58% (95% CI 11.00%-14.16%); 5.30% (4.55-6.06%), and 3.12% (2.22-4.03), respectively. Heterogeneity was high across lifetime, 12-month, and current prevalence, sex, and countries. 12-month and current prevalence was associated with higher Gini and GII, 12-month prevalence with lower HDI, and current prevalence with higher IHR. Interpretation: We found a high prevalence of ICD/DSM depressive disorders in Latin America, and a statistically significant association with inequality and development indicators. The high heterogeneity found across prevalence periods and the major gaps in country representation underscore the need to escalate efforts to improve mental health access and research capabilities in Latin America. Systematic, comparable prevalence estimates would inform more effective decision-making in the region. Funding: Pfizer Independent Medical Education Grant.
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