ArticleConservation physiology2023
Targeted metabolomics characterizes metabolite occurrence and variability in stable freshwater mussel populations.
Article in Conservation physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Omics technologies in aquafeed: unlocking the black box towards systems biology.Functional & integrative genomics · 2026Review
- Characterising Sex-Specific Metabolite Differences in New Zealand Geoduck (Animals : an open access journal from MDPI · 2025Article
- Utility of the cellular energy allocation model for assessing food limitation stress in freshwater mussels.Conservation physiology · 2025Article
- An evolving roadmap: using mitochondrial physiology to help guide conservation efforts.Conservation physiology · 2024Article
- Progress and challenges in exploring aquatic microbial communities using non-targeted metabolomics.The ISME journal · 2023Review
- Viruses of Freshwater Mussels during Mass Mortality Events in Oregon and Washington, USA.Viruses · 2023Article
- Mussel mass mortality in the Clinch River, USA: metabolomics detects affected pathways and biomarkers of stress.Conservation physiology · 2023Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Freshwater mussels (order Unionida) play a key role in freshwater systems as ecosystem engineers and indicators of aquatic ecosystem health. The fauna is globally imperilled due to a diversity of suspected factors; however, causes for many population declines and mortality events remain unconfirmed due partly to limited health assessment tools. Mussel-monitoring activities often rely on population-level measurements, such as abundance and age structure, which reflect delayed responses to environmental conditions. Measures of organismal health would enable preemptive detection of declining condition before population-level effects manifest. Metabolomic analysis can identify shifts in biochemical pathways in response to stressors and changing environmental conditions; however, interpretation of the results requires information on inherent variability of metabolite concentrations in mussel populations. We targeted metabolites in the haemolymph of two common mussels,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.