Evidence map›Paper›PMID 37701016›Full record

ArticleComputational and structural biotechnology journal2023

Performance upgrade of a microbial explosives' sensor strain by screening a high throughput saturation library of a transcriptional regulator.

Lidor David, Etai Shpigel, Itay Levin, Shaked Moshe, Lior Zimmerman, Shilat Dadon-Simanowitz, Benjamin Shemer, Shon A Levkovich, Liraz Larush, Shlomo Magdassi and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Computational and structural biotechnology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Lidor DavidEnzymit Ltd. 3 Pinhas Sapir St., Ness Ziona 7403626, Israel.
Etai ShpigelInstitute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel.
Itay LevinEnzymit Ltd. 3 Pinhas Sapir St., Ness Ziona 7403626, Israel.
Shaked MosheInstitute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel.
Lior ZimmermanEnzymit Ltd. 3 Pinhas Sapir St., Ness Ziona 7403626, Israel.
Shilat Dadon-SimanowitzInstitute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel.
Benjamin ShemerInstitute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel.
Shon A LevkovichGeorge S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 6997801, Israel.
Liraz LarushInstitute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel.
Shlomo MagdassiInstitute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel.
Shimshon BelkinEnzymit Ltd. 3 Pinhas Sapir St., Ness Ziona 7403626, Israel.
Hebrew University of Jerusalem · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a methodology for a high-throughput screening (HTS) of transcription factor libraries, based on bacterial cells and GFP fluorescence. The method is demonstrated on the

Indexed as

BioluminescenceBioreportersEscherichia coliHigh-throughput screen (HTS)LandminesNGSPrecision Mutant LibraryProtein engineeringWhole-cell biosensors

Identifiers

PMID37701016
PMCPMC10493890
OpenAlexW4386057278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.