Evidence map›Paper›PMID 37700886›Full record

ArticleEuropean journal of obstetrics & gynecology and reproductive biology: X2023

Seminal biomarkers and their correlations to semen parameters in subfertile men.

Sabrina Lasini Gruhl, Lee Mee Ho, Marris Yin Xuan Sim, Shaw Ni Lee, Su Ling Yu, Tze Tein Yong, Liqing Serene Lim, Hemashree Rajesh

Open access · goldAbstract read
In one paragraph

Article in European journal of obstetrics & gynecology and reproductive biology: X, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sabrina Lasini GruhlDepartment of Obstetrics and Gynaecology, Outram Rd, 169608, Singapore.
Lee Mee HoDepartment of Obstetrics and Gynaecology, Outram Rd, 169608, Singapore.
Marris Yin Xuan SimDepartment of Obstetrics and Gynaecology, Outram Rd, 169608, Singapore.
Shaw Ni LeeDepartment of Obstetrics and Gynaecology, Outram Rd, 169608, Singapore.
Su Ling YuDepartment of Obstetrics and Gynaecology, Outram Rd, 169608, Singapore.
Tze Tein YongDepartment of Obstetrics and Gynaecology, Outram Rd, 169608, Singapore.
Liqing Serene LimDepartment of Obstetrics and Gynaecology, Outram Rd, 169608, Singapore.
Hemashree RajeshDepartment of Obstetrics and Gynaecology, Outram Rd, 169608, Singapore.
Singapore General Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research question: To assess the levels of seminal biomarkers fructose, zinc and citrate and their correlations to semen parameters in infertile men. Design: 200 infertile male participants undergoing fertility assessment at Singapore General Hospital (SGH), Singapore were recruited prospectively, from June 2020 to August 2021. Their semen samples were assessed for seminal parameters, biomarker levels of fructose, citrate and zinc, leukocyte concentrations and aerobic cultures. They were also assessed for their smoking habits. Results: Sperm concentrations were negatively correlated to seminal fructose levels, Conclusions: Higher zinc and citrate levels correlated with better progressive motility, sperm morphology and TMSC. Smoking negatively impacted zinc and citrate levels, thereby affecting sperm quality. In conclusion, the inclusion of biomarkers in basic male work-up assessment would assist in identifying common deficiencies and aid in adequate replacement therapy.

Indexed as

CitrateMale infertilitySeminal biomarkersSeminal fructose levelsSmokingZinc

Identifiers

PMID37700886
PMCPMC10493244
OpenAlexW4386365575

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.