Evidence map›Paper›PMID 37700549›Full record

Observational studyHealth services research2023

Evaluating a health system-wide opioid disposal intervention distributing home-disposal bags.

Lyen C Huang, Josh Bleicher, Michael Torre, Jordan E Johnson, Angela Presson, Morgan M Millar, Adam J Gordon, Benjamin S Brooke, Kimberly A Kaphingst, Alex H S Harris

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Health services research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lyen C HuangDepartment of Surgery, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0002-8605-2631
Josh BleicherDepartment of Surgery, University of Utah, Salt Lake City, Utah, USA.
Michael TorreDepartment of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Jordan E JohnsonDepartment of Surgery, University of Utah, Salt Lake City, Utah, USA.
Angela PressonDepartment of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Morgan M MillarDepartment of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Adam J GordonProgram for Addiction Research, Clinical Care, Knowledge and Advocacy (PARCKA), Division of Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Benjamin S BrookeDepartment of Surgery, University of Utah, Salt Lake City, Utah, USA.
Kimberly A KaphingstHuntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
Alex H S HarrisDepartment of Surgery, Stanford University, Stanford, California, USA.
University of Utah · USVA Palo Alto Health Care System · US

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
CTSA UM1 Program at University of UtahUM1TR004409 · NCATS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI RACHEL HESS, Jennifer Juhl Majersik · 2023 to 2026
$21.9M
Greater Intermountain Node (CTN-0151)UG1DA049444 · NIDA · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Gerald T. Cochran, Adam Joseph Gordon · 2019 to 2026
$16.8M
Vascular Health and Risk Factors in Children with Down SyndromeKL2TR002539 · NCATS · UNIVERSITY OF UTAH · PI MURTAUGH, MAUREEN A, NYGAARD, INGRID E · 2018 to 2022
$4.3M
NCATS NIH HHS KL2 TR002539NCATS NIH HHS UL1 TR002538NCATS NIH HHS UM1 TR004409NIDA NIH HHS UG1 DA049444
6 · The paper itself

Abstract

objectiveTo evaluate a health system-wide intervention distributing free home-disposal bags to surgery patients prescribed opioids. DATA SOURCES AND STUDY

settingWe collected patient surveys and electronic medical record data at an academic health system. STUDY

designWe conducted a prospective observational study. The bags were primarily distributed at pharmacies, though pharmacists delivered bags to some patients. The primary outcome was disposal of leftover opioids (effectiveness). Secondary outcomes were patient willingness to dispose and factors associated with disposal (effectiveness), recalling receipt of the bag (reach), and recalling receipt of bags and disposal over time (maintenance). We used a modified Poisson regression to evaluate the relative risk of disposal. Inverse probability of treatment weighting, based on propensity scores, was used to account for differences between survey responders and non-responders and reduce nonresponse bias. DATA COLLECTION/EXTRACTION

methodsFrom August 2020 to May 2021, we surveyed patients 2 weeks after discharge (allowing for home opioid use). Eligibility criteria were age ≥18, English being primary language, valid email address, hospitalization ≤30 days, discharge home, and an opioid prescription sent to a system pharmacy. PRINCIPAL

findingsWe identified 5134 patients with 2174 completing the survey (response rate 42.3%). Among respondents, 1375 (63.8%) recalled receiving the disposal bag. Among 1075 respondents with leftover opioids, 284 (26.4%) disposed, 552 (51.3%) planned to dispose, 79 (7.4%) did not plan to dispose, 69 (6.4%) had undecided, and 91 (8.5%) had not considered disposal. Recalling receipt of the bag (incidence rate ratio [IRR] 1.25, 95% confidence interval [CI] 1.13-1.37) was positively associated with disposal. Patients who used opioids in the last year were less likely to dispose (IRR 0.82, 95% CI 0.73-0.93). Disposal rates remained stable over the study period while recalling receipt of bags trended up.

conclusionsA pragmatic implementation of a disposal intervention resulted in lower disposal rates than prior trials.

Indexed as

Analgesics, OpioidOpioid-Related DisordersAdolescentAdultHospitalizationHumansPatient DischargeProspective StudiesAnalgesics, Opioidhealth system interventionimplementationopioidsprevention of opioid-related harmssurgery

Identifiers

PMID37700549
PMCPMC10622267
OpenAlexW4386704288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.