ArticleInfection control and hospital epidemiology2023
Impact of measurement and feedback on chlorhexidine gluconate bathing among intensive care unit patients: A multicenter study.
Article in Infection control and hospital epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07039955 (Effectiveness of Daily Chlorhexidine Bathing and Antibiotic and Proton Pump Inhibitor), which is not on this map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Daily Chlorhexidine Bathing and Antibiotic and Proton Pump Inhibitor (PPI) Stewardship in Preventing Transmission and Infection Caused by Carbapenemase-Producing Enterobacteriaceae (CPE)
Who cites it
6 citing papers in PubMed, 5 citations in OpenAlex.
- Transfer ofOpen forum infectious diseases · 2026Article
- Can Chlorhexidine Bathing Reduce Candidozyma auris Shedding?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Article
- Are high residual chlorhexidine skin concentrations associated with improved clinical outcomes? Lessons from the CLEAR trial.Infection control and hospital epidemiology · 2026Article
- Can chlorhexidine gluconate baths reduce fungal colonisation in intensive care unit patients?Antimicrobial resistance and infection control · 2025Article
- Relationship between chlorhexidine gluconate concentration and microbial colonization of patients' skin.Infection control and hospital epidemiology · 2024Article
- Rapid Environmental Contamination With Candida auris and Multidrug-Resistant Bacterial Pathogens Near Colonized Patients.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 8 institutions in 1 country.
Funding
Abstract
objectiveTo assess whether measurement and feedback of chlorhexidine gluconate (CHG) skin concentrations can improve CHG bathing practice across multiple intensive care units (ICUs).
designA before-and-after quality improvement study measuring patient CHG skin concentrations during 6 point-prevalence surveys (3 surveys each during baseline and intervention periods).
settingThe study was conducted across 7 geographically diverse ICUs with routine CHG bathing.
participantsAdult patients in the medical ICU.
methodsCHG skin concentrations were measured at the neck, axilla, and inguinal region using a semiquantitative colorimetric assay. Aggregate unit-level CHG skin concentration measurements from the baseline period and each intervention period survey were reported back to ICU leadership, which then used routine education and quality improvement activities to improve CHG bathing practice. We used multilevel linear models to assess the impact of intervention on CHG skin concentrations.
resultsWe enrolled 681 (93%) of 736 eligible patients; 92% received a CHG bath prior to survey. At baseline, CHG skin concentrations were lowest on the neck, compared to axillary or inguinal regions (
conclusionsRoutine CHG bathing performance in the ICU varied across multiple hospitals. Measurement and feedback of CHG skin concentrations can be an important tool to improve CHG bathing practice.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.