ArticleBMC musculoskeletal disorders2023
Establishment and validation of a nomogram for predicting new fractures after PKP treatment of for osteoporotic vertebral compression fractures in the elderly individuals.
Article in BMC musculoskeletal disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
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13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 10 citations in OpenAlex.
- Prediction models for subsequent vertebral fractures after percutaneous vertebroplasty or kyphoplasty: a systematic review and critical appraisal.BMC musculoskeletal disorders · 2026Pooled it
- Risk factors for new vertebral compression fracture following percutaneous vertebral augmentation: a systematic review and meta-analysis based on multivariate logistic regression analysis.Journal of orthopaedic surgery and research · 2025Pooled it
- Risk factors for new vertebral fracture after percutaneous vertebroplasty or kyphoplasty for osteoporotic vertebral compression fractures (OVCFs): an updated systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Pooled it
- Interpretable machine learning model integrating MRI-derived paraspinal muscle parameters for predicting new vertebral compression fractures after vertebral augmentation.European radiology · 2026Article
- Risk Prediction Models for New Vertebral Fracture After Vertebral Augmentation in Elderly Patients with Osteoporotic Vertebral Compression Fractures: A Systematic Review.Healthcare (Basel, Switzerland) · 2026Review
- Review
- Analysis of risk factors and development of a predictive model for new vertebral fractures subsequent to percutaneous kyphoplasty in patients with single-segment osteoporotic vertebral compression fractures.BMC musculoskeletal disorders · 2026Article
- Risk factors analysis for refracture after vertebroplasty in osteoporotic thoracolumbar vertebral fractures.European journal of medical research · 2025Article
- Development and validation of a prediction model for new vertebral fracture after percutaneous kyphoplasty.Scientific reports · 2025Article
- Percutaneous kyphoplasty improves surgical outcomes and quality of life in elderly patients with osteoporotic vertebral compression fractures.American journal of translational research · 2025Article
- Deep Learning for Discrimination of Early Spinal Tuberculosis from Acute Osteoporotic Vertebral Fracture on CT.Infection and drug resistance · 2025Article
- Construction of a nomogram to predict the probability of new vertebral compression fractures after vertebral augmentation of osteoporotic vertebral compression fractures: a retrospective study.Frontiers in medicine · 2024Article
- Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate the risk factors for new vertebral compression fractures (NVCFs) after percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fractures (OVCFs) and to create a nomogram to predict the occurrence of new postoperative fractures.
methodsThis was a retrospective analysis of the clinical data of 529 OVCF patients who received PKP treatment in our hospital from June 2017 to June 2020. Based on whether there were new fractures within 2 years after surgery, the patients were divided into a new fracture group and a nonnew fracture group. Univariate and multivariate analyses were used to determine the risk factors for the occurrence of NVCFs after surgery. The data were randomly divided into a training set (75%) and a testing set (25%). Nomograms predicting the risk of NVCF occurrence were created based on the results of the multivariate analysis, and performance was evaluated using receiver operating characteristic curves (ROCs), calibration curves, and decision curve analyses (DCAs). A web calculator was created to give clinicians a more convenient interactive experience.
resultsA total of 56 patients (10.6%) had NVCFs after surgery. The univariate analysis showed significant differences in sex and the incidences of cerebrovascular disease, a positive fracture history, and bone cement intervertebral leakage between the two groups (P < 0.05). The multivariate analysis showed that sex [OR = 2.621, 95% CI (1.030-6.673), P = 0.043], cerebrovascular disease [OR = 28.522, 95% CI (8.749-92.989), P = 0.000], fracture history [OR = 12.298, 95% CI (6.250-24.199), P = 0.000], and bone cement intervertebral leakage [OR = 2.501, 95% CI (1.029-6.082), P = 0.043] were independent risk factors that were positively associated with the occurrence of NVCFs. The AUCs of the model were 0.795 (95% CI: 0.716-0.874) and 0.861 (95% CI: 0.749-0.974) in the training and testing sets, respectively, and the calibration curves showed high agreement between the predicted and actual states. The areas under the decision curve were 0.021 and 0.036, respectively.
conclusionFemale sex, cerebrovascular disease, fracture history and bone cement intervertebral leakage are risk factors for NVCF after PKP. Based on this, a highly accurate nomogram was developed, and a webpage calculator ( https://new-fracture.shinyapps.io/DynNomapp/ ) was created.
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