Evidence map›Paper›PMID 37700267›Full record

ArticlePediatric rheumatology online journal2023

The impact of the COVID-19 pandemic on patients with juvenile idiopathic inflammatory myopathies.

Dawn M Wahezi, Dominique Jerome, Evin Rothschild, Belina Yi, Jeffrey Dvergsten, Stacey Tarvin, Susan Kim, Tamar Rubinstein, CARRA JDM workgroup

Open access · goldAbstract read
In one paragraph

Article in Pediatric rheumatology online journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Dawn M WaheziDivision of Pediatric Rheumatology, Children's Hospital at Montefiore, 3415 Bainbridge Avenue, Bronx, NY, USA. dwahezi@montefiore.org.
Dominique JeromeDivision of Pediatric Rheumatology, Children's Hospital at Montefiore, 3415 Bainbridge Avenue, Bronx, NY, USA.
Evin RothschildDivision of Pediatric Rheumatology, Children's Hospital at Montefiore, 3415 Bainbridge Avenue, Bronx, NY, USA.
Belina YiChildren's Hospital Los Angeles, Los Angeles, CA, USA.
Jeffrey DvergstenDuke Children's Health Center, Durham, NC, USA.
Stacey TarvinRiley Children's Health, Indianapolis, IN, USA.
Susan KimUCSF Benioff Children's Hospital, San Francisco, CA, USA.
Tamar RubinsteinDivision of Pediatric Rheumatology, Children's Hospital at Montefiore, 3415 Bainbridge Avenue, Bronx, NY, USA.
CARRA JDM workgroup
Children's Hospital at Montefiore · USChildren's Hospital of Los Angeles · USDuke Children's Hospital & Health Center · USRiley Hospital for Children · USUCSF Benioff Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThroughout the COVID-19 pandemic, there have been concerns regarding the risks of infection in patients with autoimmune disease. In this study, we investigated the impact of the pandemic on patients with juvenile idiopathic inflammatory myopathies (JIIM).

methodsData were collected using a patient/caregiver survey via Research Electronic Data Capture (REDCap) database. Eligibility included JIIM diagnosis and current age less than 21 years old. Surveys were distributed via the CureJM organization, social media, Childhood Arthritis and Rheumatology Research Alliance (CARRA) network and Dr. Peter Dent Pediatric Rheumatology Bulletin Board.

resultsEighty-four respondents accessed the survey, 70 (83%) consented to participate, and 54 out of 70 completed the full survey (77%). Twenty-seven out of 57 patients (47%) tested positive for COVID-19, with 7 (12%) testing positive more than once. Despite broad usage of immunosuppressive medications, 24 out of 27 (89%) reported mild symptoms with none requiring hospitalization. Four patients reported a flare of JIIM symptoms after COVID-19; three of whom held immunomodulatory medications during their infection. Thirty-seven out of 54 respondents (69%) reported vaccination against COVID-19, with 9 out of 37 (24%) reporting minor vaccine side effects and one reporting JIIM flare post vaccination. Twenty-one out of 54 (39%) respondents reported psychosocial concerns related to the COVID-19 pandemic.

conclusionsPatients with JIIM, including those on multiple immunosuppressive medications, had mild symptoms related to COVID-19. Most patients tolerated COVID-19 vaccination well. Few patients had disease flare post-COVID-19 or vaccination. Mental health concerns were demonstrated in JIIM patients during the COVID-19 pandemic.

Indexed as

Arthritis, JuvenileCOVID-19MyositisAdultChildCOVID-19 VaccinesHumansPandemicsYoung AdultCOVID-19 VaccinesJuvenile idiopathic inflammatory myopathiesPediatric rheumatology

Identifiers

PMID37700267
PMCPMC10496159
OpenAlexW4386689653

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.