Evidence map›Paper›PMID 37700238›Full record

ArticleBMC gastroenterology2023

A radiomics model fusing clinical features to predict microsatellite status preoperatively in colorectal cancer liver metastasis.

Xuehu Wang, Ziqi Liu, Xiaoping Yin, Chang Yang, Jushuo Zhang

Open access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Liver metastases beyond classical imaging findings.Abdominal radiology (New York) · 2026
    Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Xuehu WangCollege of Electronic and Information Engineering, Hebei University, Baoding, 071002, China. wangxuehu_tougao@163.com.
Ziqi LiuCollege of Electronic and Information Engineering, Hebei University, Baoding, 071002, China.
Xiaoping YinAffiliated Hospital of Hebei University, Bao Ding, 071000, China.
Chang YangCollege of Electronic and Information Engineering, Hebei University, Baoding, 071002, China.
Jushuo ZhangCollege of Electronic and Information Engineering, Hebei University, Baoding, 071002, China.
Hebei University · CNAffiliated Hospital of Hebei University · CNHebei Mental Health Center · CN

Funding

China Postdoctoral Fund 2018M631755Hebei Province High-level Talent Funding Project-Post-doctoral Research Projects Selective Funding B2018003002Hebei provincial government funded Provincial Medical Talents Project in 2020 ,CT radiomics study on the correlation between CRLM and microsatellite instability 361007. 8.Medical discipline cultivation project of Hebei University in 2020,CT radiomics study on the correlation between CRLM and microsatellite instability 2020B05Hebei University improve comprehensive strength special funds in the Midwest 801260201011National Natural Science Foundation of China 61401308 and 61572063Natural Science Foundation of Gansu Province 18JR3RA029Natural Science Foundation of Hebei Province, General Project H2020201021Nature Science Foundation of Hebei H202101017Outstanding young scientific research and innovation team of Hebei University 605020521007
6 · The paper itself

Abstract

purposeTo study the combined model of radiomic features and clinical features based on enhanced CT images for noninvasive evaluation of microsatellite instability (MSI) status in colorectal liver metastasis (CRLM) before surgery.

methodsThe study included 104 patients retrospectively and collected CT images of patients. We adjusted the region of interest to increase the number of MSI-H images. Radiomic features were extracted from these CT images. The logistic models of simple clinical features, simple radiomic features, and radiomic features with clinical features were constructed from the original image data and the expanded data, respectively. The six models were evaluated in the validation set. A nomogram was made to conveniently show the probability of the patient having a high MSI (MSI-H).

resultsThe model including radiomic features and clinical features in the expanded data worked best in the validation group.

conclusionA logistic regression prediction model based on enhanced CT images combining clinical features and radiomic features after increasing the number of MSI-H images can effectively identify patients with CRLM with MSI-H and low-frequency microsatellite instability (MSI-L), and provide effective guidance for clinical immunotherapy of CRLM patients with unknown MSI status.

Indexed as

Colorectal NeoplasmsLiver NeoplasmsHumansMicrosatellite InstabilityMicrosatellite RepeatsRetrospective StudiesLiver metastasis of colorectal cancerLogistic regressionMicrosatellite instabilityNomogramRadiomics

Identifiers

PMID37700238
PMCPMC10498531
OpenAlexW4386691550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.