Evidence map›Paper›PMID 37700223›Full record

SynthesisBMC infectious diseases2023

Global prevalence of asymptomatic norovirus infection in outbreaks: a systematic review and meta-analysis.

Jun Wang, Zhao Gao, Zu-Rong Yang, Kun Liu, Hui Zhang

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Epidemiology of Norovirus Outbreaks in Kindergartens, Primary Schools, and Junior High Schools in Xi'an, China, From October 2020 to February 2023.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Impact of Nanoparticle-Based TiOFoods (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jun WangDepartment of Clinical Laboratory, Jiaozhou Central Hospital, 29 Xuzhou Road, Qingdao, Shandong, 266300, P.R. China.
Zhao GaoDepartment of Clinical Laboratory, Jinan Second Peoples' Hospital, 148 Jingyi Road, Jinan, Shandong, 250000, P.R. China.
Zu-Rong YangDepartment of Epidemiology, Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Air Force Medical University, 169 Changle west Road, Xi'an, Shaanxi, 710032, P.R. China.
Kun LiuDepartment of Epidemiology, Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Air Force Medical University, 169 Changle west Road, Xi'an, Shaanxi, 710032, P.R. China. liukun5959@qq.com.ORCID http://orcid.org/0000-0003-1847-8208
Hui ZhangDepartment of Prevention of Infectious Diseases, Xi'an Center for Disease Control and Prevention, 599 Xiying Road, Xi'an, Shaanxi, 710054, P.R. China. 493490422@qq.com.ORCID http://orcid.org/0000-0002-8251-8983

Funding

National Natural Science Foundation of China 81803289Natural Science Basic Research Project of Shaanxi Province 2020JM-329Natural Science Basic Research Project of Shaanxi Province 2020JQ-969
6 · The paper itself

Abstract

backgroundAlthough many studies on asymptomatic norovirus infection in outbreaks have been conducted globally, structured data (important for emergency management of outbreaks) on the prevalence of this epidemic are still not available. This study assessed the global prevalence of asymptomatic norovirus infection in outbreaks.

methodsWe identified publications on asymptomatic infections from norovirus outbreaks by searching the PubMed, Embase, Cochrane Library, Medline, and Web of Science databases and screening references from the articles reviewed. Prevalence of asymptomatic norovirus infection in outbreaks was employed as the primary summary data. The random-effects model of the meta-analysis was fitted to generate estimates of the prevalence in the overall and subgroup populations.

resultsIn total, 44 articles with a sample size of 8,115 asymptomatic individuals were included. The estimated pooled prevalence of asymptomatic norovirus infection in outbreaks was 21.8% (95%CI, 17.4-27.3). The asymptomatic prevalence of norovirus GII (20.1%) was similar to that of GI (19.8%); however, the proportion prevalence of asymptomatic individuals involved in the former (33.36%) was significantly higher than that of in the latter (0.92%) and the former (93.18%) was reported much more frequently than the latter (15.91%) in the included articles. These studies had significant heterogeneity (I

conclusionsThe overall pooled asymptomatic prevalence of norovirus in outbreaks was high, with genome II dominating. Asymptomatic individuals may play an important role in norovirus outbreaks. This knowledge could help in developing control strategies and public health policies for norovirus outbreaks.

Indexed as

EpidemicsNorovirusAsymptomatic InfectionsDisease OutbreaksHumansPrevalenceAsymptomaticMeta-analysisNorovirusOutbreaksPrevalence

Identifiers

PMID37700223
PMCPMC10496210

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.