Evidence map›Paper›PMID 37699744›Full record

ArticleBMJ case reports2023

Metastatic paraganglioma presenting with spinal cord compression requiring urgent surgery.

Zachary Gauci, Miriam Giordano Imbroll, Ebony Sciberras Giusti, Shawn Agius, Mark Gruppetta

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 74% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zachary GauciDepartment of Endocrinology and General Medicine, Mater Dei Hospital, Msida, Malta zachary.gauci@gov.mt.
Miriam Giordano ImbrollDepartment of Endocrinology and General Medicine, Mater Dei Hospital, Msida, Malta.
Ebony Sciberras GiustiDepartment of Endocrinology and General Medicine, Mater Dei Hospital, Msida, Malta.
Shawn AgiusDepartment of Neurosciences, Mater Dei Hospital, Msida, Malta.
Mark GruppettaDepartment of Endocrinology and General Medicine, Mater Dei Hospital, Msida, Malta.ORCID http://orcid.org/0000-0002-5627-6511
Mater Dei Hospital · MT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a rare case of a functional bladder paraganglioma diagnosed in a young man who presented with acute compressive thoracic myelopathy secondary to vertebral metastasis. A histological diagnosis of a metastatic paraganglioma was made following biopsy of a rib lesion. CT revealed a lesion in the inferior wall of the bladder, which demonstrated avid uptake on 68Ga-DOTATATE PET/CT. Serum metanephrine levels were more than 40 times the upper limit of normal. The patient was hypertensive and treatment with doxazosin was initiated. In view of neurological deterioration, he required urgent spinal decompression to preserve neurological function and prevent permanent paraplegia. Despite inadequate alpha-blockade, surgery was successful, and the perioperative course was uneventful. Alpha-blockade was subsequently optimised. Treatment with cyclophosphamide, vincristine and dacarbazine was started but, in view of disease progression, treatment was subsequently changed to sunitinib.

Indexed as

Adrenal Gland NeoplasmsBrain NeoplasmsParagangliomaSpinal Cord CompressionBiopsyHumansMalePositron Emission Tomography Computed TomographyAdrenal disordersCancerNeurosurgerySpinal cord

Identifiers

PMID37699744
PMCPMC10503315
OpenAlexW4386629795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.