Evidence map›Paper›PMID 37699706›Full record

ArticleeNeuro2023

Pupil Size Is Sensitive to Low-Level Stimulus Features, Independent of Arousal-Related Modulation.

June Hee Kim, Christine Yin, Elisha P Merriam, Zvi N Roth

Abstract read
In one paragraph

Article in eNeuro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Benefits of Dual-Tasking on Implicit Sensorimotor Adaptation.The European journal of neuroscience · 2026
    Article
  4. Heterogeneous Effects of Cognitive Arousal on the Contrast Response in Human Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  5. Frontotemporal network contribution to occluded face processing.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

June Hee KimLaboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892.
Christine YinLaboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892.
Elisha P MerriamLaboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892.
Zvi N RothLaboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 zvi.roth@nih.gov.

Funding

Multiple Scales of Stimulus Representation in the Human BrainZIAMH002966 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI MERRIAM, ELISHA · 2017 to 2025
$10.5M
Intramural NIH HHS ZIA MH002966
6 · The paper itself

Abstract

Similar to a camera aperture, pupil size adjusts to the surrounding luminance. Unlike a camera, pupil size is additionally modulated both by stimulus properties and by cognitive processes, including attention and arousal, though the interdependence of these factors is unclear. We hypothesized that different stimulus properties interact to jointly modulate pupil size while remaining independent from the impact of arousal. We measured pupil responses from human observers to equiluminant stimuli during a demanding rapid serial visual presentation (RSVP) task at fixation and tested how response amplitude depends on contrast, spatial frequency, and reward level. We found that under constant luminance, unattended stimuli evoke responses that are separable from changes caused by general arousal or attention. We further uncovered a double-dissociation between task-related responses and stimulus-evoked responses, suggesting that different sources of pupil size modulation are independent of one another. Our results shed light on neural pathways underlying pupillary response.

Indexed as

ArousalPupilAttentionHumansPhotic StimulationVision, Oculararousalarousal-linked pupil responseattentionpupilrewardtask-related pupil response

Identifiers

PMID37699706
PMCPMC10585606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.