Evidence map›Paper›PMID 37699653›Full record

ArticleAnnals of the rheumatic diseases2024

HLA-DRB1 and HLA-DQA1 associated with immunogenicity to adalimumab therapy in patients with rheumatoid arthritis.

Chuan Fu Yap, Nisha Nair, Annick de Vries, Floris C Loeff, Ann W Morgan, John D Isaacs, Anthony G Wilson, Kimme L Hyrich, Anne Barton, Darren Plant

Open access · hybridAbstract readLetter
In one paragraph

Article in Annals of the rheumatic diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Chuan Fu YapCentre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK.ORCID http://orcid.org/0000-0001-5256-5642
Nisha NairCentre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK.
Annick de VriesDiagnostic Services, Sanquin, Amsterdam, The Netherlands.
Floris C LoeffDiagnostic Services, Sanquin, Amsterdam, The Netherlands.
Ann W MorganSchool of Medicine, University of Leeds, Leeds, UK.ORCID http://orcid.org/0000-0003-1109-624X
John D IsaacsTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.ORCID http://orcid.org/0000-0002-6103-7056
Anthony G WilsonSchool of Medicine and Medical Science, Conway Institute, University College Dublin, University College Dublin, Dublin, Ireland.ORCID http://orcid.org/0000-0003-4855-3926
Kimme L HyrichNIHR Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Anne BartonCentre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK.ORCID http://orcid.org/0000-0003-3316-2527
Darren PlantCentre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK Darren.Plant@manchester.ac.uk.ORCID http://orcid.org/0000-0003-1395-9344
Manchester Academic Health Science Centre · GBSanquin · NLUniversity of Manchester · GBNewcastle upon Tyne Hospitals NHS Foundation Trust · GBUniversity College Dublin · IEUniversity of Leeds · GB

Funding

Medical Research Council G1001518Medical Research Council MR/K015346/1Versus Arthritis 21173Versus Arthritis 21755
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Arthritis, RheumatoidAdalimumabAllelesAutoantibodiesGenetic Predisposition to DiseaseHLA-DQ alpha-ChainsHLA-DRB1 ChainsHumansAdalimumabAutoantibodiesHLA-DQA1 antigenHLA-DQ alpha-ChainsHLA-DRB1 ChainsAdalimumabArthritis, RheumatoidAutoantibodiesMethotrexate

Identifiers

PMID37699653
PMCPMC10850714
OpenAlexW4386636387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.