Evidence map›Paper›PMID 37699166›Full record

ArticleOcular immunology and inflammation2024

Diagnosis and Characteristics of Presentation of Tubulointerstitial Nephritis and Uveitis Syndrome During the COVID-2019 Pandemic.

Lingling Huang, David Ta Kim, Christopher R Rosenberg, Phoebe Lin, Eric Suhler

Open access · greenAbstract read
In one paragraph

Article in Ocular immunology and inflammation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Lingling HuangCasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.ORCID 0000-0002-8305-1035
David Ta KimCasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.ORCID 0000-0002-2604-6205
Christopher R RosenbergCasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.ORCID 0000-0002-0955-8452
Phoebe LinCasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.
Eric SuhlerCasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.
Oregon Health & Science University · USCleveland Clinic · USUniversity of British Columbia · CA

Funding

Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Kate E Keller · 1995 to 2026
$19.4M
Intestinal T cells and microbiota as therapeutic targets in autoimmune uveitisR01EY032882 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI LIN, PHOEBE · 2021 to 2025
$2.5M
The effect of the microbiome on the development and severity of uveitisK08EY022948 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI LIN, PHOEBE · 2013 to 2017
$1.0M
NEI NIH HHS K08 EY022948NEI NIH HHS P30 EY010572NEI NIH HHS R01 EY032882
6 · The paper itself

Abstract

purposeTo compare the diagnosis and clinical features of tubulointerstitial nephritis and uveitis syndrome (TINU) before and during the COVID-19 pandemic.

methodsRetrospective chart review.

resultsBefore the COVID-19 pandemic (March 2017 to March 2019), 1/561 (0.18%) new patient was diagnosed with TINU. During the pandemic (March 2020 to March 2022), 15/581 (2.58%) new patients were diagnosed with TINU. We found a significant increase in TINU cases during the pandemic (P=0.0005). Various posterior segment findings were observed in 2/3 (66.7%) patients before the pandemic and 13/15 (86.7%) patients during the pandemic, including disc edema, chorioretinal scars, disc leakage, and peripheral vascular leakage.

conclusionThis is the first study reporting an increased number of TINU during the COVID-19 pandemic. With most of the American population now exposed to COVID-19, a large multi-center epidemiological study would be helpful to investigate any association of COVID-19 disease or vaccination with TINU in recent years.

Indexed as

COVID-19Nephritis, InterstitialSARS-CoV-2UveitisAdolescentAdultAgedFemaleHumansMaleMiddle AgedPandemicsRetrospective StudiesTomography, Optical CoherenceYoung AdultCOVID-19diagnosis and treatmentpediatric uveitistubulointerstitial nephritis and uveitis syndrome, TINUuveitis

Identifiers

PMID37699166
PMCPMC10927609
OpenAlexW4386631981

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.