Evidence map›Paper›PMID 37698935›Full record

ArticlePerfusion2024

Evaluation of a new magnetically suspended centrifugal neonatal pump in healthy animals using a veno-venous extracorporeal membrane oxygenation configuration.

Matteo Di Nardo, Anthony Moreau, Filippo Annoni, Fuhong Su, Mirko Belliato, Lars Mikael Broman, Maximilian Malfertheiner, Roberto Lorusso, Fabio Silvio Taccone

Open access · hybridAbstract read
In one paragraph

Article in Perfusion, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 5 countries.

Matteo Di NardoPediatric Intensive Care Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.ORCID 0000-0003-0051-8080
Anthony MoreauDepartment of Intensive Care, Erasme Hospital, Brussels, Belgium.
Filippo AnnoniDepartment of Intensive Care, Erasme Hospital, Brussels, Belgium.
Fuhong SuDepartment of Intensive Care, Erasme Hospital, Brussels, Belgium.
Mirko BelliatoSC AR2 Anestesia e Terapia Intensiva Cardiotoracica, Foundation IRCCS, Policlinico San Matteo, Pavia, Italy.
Lars Mikael BromanDepartment of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
Maximilian MalfertheinerInternal Medicine II, University of Regensburg, Regensburg, Germany.ORCID 0000-0002-6245-2614
Roberto LorussoHeart & Vascular Centre, Maastricht University Medical Centre, Maastricht, The Netherlands.ORCID 0000-0002-1777-2045
Fabio Silvio TacconeDepartment of Intensive Care, Erasme Hospital, Brussels, Belgium.
Université Libre de Bruxelles · BEBambino Gesù Children's Hospital · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITKarolinska University Hospital · SEMaastricht University Medical Centre · NLUniversity of Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe objective of this animal study was to evaluate the hemodynamic performance of a new centrifugal pump for extra-corporeal membrane oxygenation (ECMO) support in neonates.

methodsSix healthy swines were supported with veno-venous ECMO with the New Born ECMOLife centrifugal pump (Eurosets, Medolla, Italy) at different flow rates: 0.25, 0.5, 0.6, and 0.8 L/min; three animals were evaluated at low-flows (0.25 and 0.5 L/min) and three at high-flows (0.6 and 0.8 L/min). Each flow was maintained for 4 hours. Blood samples were collected at different time-points. Hematological and biochemical parameters and ECMO parameters [flow, revolutions per minute (RPM), drainage pressure, and the oxygenator pressure drop] were evaluated.

resultsThe increase of the pump flow from 0.25 to 0.5 L/min or from 0.6 to 0.8 L/min required significantly higher RPM and produced significantly higher pump pressures [from 0.25 to 0.5 L/min: 1470 (1253-1569) versus 2652 (2589-2750) RPM and 40 (26-57) versus 125 (113-139) mmHg, respectively;

conclusionsIn this animal study, the "New Born ECMOLife" centrifugal pump showed good hemodynamic performance. Long-term studies are needed to evaluate biocompatibility of this new ECMO pump.

Indexed as

Extracorporeal Membrane OxygenationAnimalsAnimals, NewbornHeart-Assist DevicesHemodynamicsHumansSwinecentrifugal pumpextracorporeal membrane oxygenationhemolysismagnetical levitationneonatenewborn

Identifiers

PMID37698935
PMCPMC11445975
OpenAlexW4386691245

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.