Evidence map›Paper›PMID 37698853›Full record

ArticleGut microbes2023

Host miR-129-5p reverses effects of ginsenoside Rg1 on morphine reward possibly mediated by changes in

Chan Li, Yingbo Lin, Rukun Lin, Zhijie Chen, Qichun Zhou, Chaohua Luo, Zhixian Mo

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chan LiSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Yingbo LinSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Rukun LinSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Zhijie ChenSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Qichun ZhouSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Chaohua LuoSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Zhixian MoSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Southern Medical University · CNJiangmen Central Hospital · CNZhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Morphine addiction is closely associated with dysbiosis of the gut microbiota. miRNAs play a crucial role in regulating intestinal bacterial growth and are involved in the development of disease. Ginsenoside Rg1 exhibits an anti-addiction effect and significantly improves intestinal microbiota disorders. In pseudo-germfree mice, supplementation with

Indexed as

Gastrointestinal MicrobiomeMicroRNAsMorphineAnimalsBacteroidesGinsenosidesHippocampusMiceRewardSerotoninginsenoside Rg1GinsenosidesMicroRNAsMIRN129 microRNA, mouseMorphineSerotoninBacteroides vulgatusginsenoside Rg1gut microbiotamiR-129-5pMorphine

Identifiers

PMID37698853
PMCPMC10498813
OpenAlexW4386623998

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.