Evidence map›Paper›PMID 37697423›Full record

Observational studyInfectious diseases of poverty2023

Impact factors of Blastocystis hominis infection in persons living with human immunodeficiency virus: a large-scale, multi-center observational study from China.

Shun-Xian Zhang, Ji-Chun Wang, Zhong-Wei Li, Jin-Xin Zheng, Wen-Ting Zhou, Guo-Bing Yang, Ying-Fang Yu, Xiu-Ping Wu, Shan Lv, Qin Liu and 12 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Infectious diseases of poverty, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Cardiovascular system characteristics in HIV/AIDS patients with talaromycosis.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Article
  3. Observational
  4. AnthropogenicMicroorganisms · 2025
    Article
  5. Atypical Presentation ofInternational medical case reports journal · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 9 institutions in 1 country.

Shun-Xian Zhang *Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.
Ji-Chun Wang *Department of Science and Technology, Chinese Center for Disease Control and Prevention, Beijing, 102206, China.
Zhong-Wei Li *Gansu Province People's Hospital, Gansu Provincial Hospital, Lanzhou, 730000, China.
Jin-Xin ZhengChinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research On Tropical Diseases, National Institute of Parasitic Diseases, Shanghai, 200025, China.
Wen-Ting ZhouNational Health Commission (NHC) Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China.
Guo-Bing YangGansu Provincial Center for Disease Control and Prevention, Lanzhou, 730000, China.
Ying-Fang YuChinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research On Tropical Diseases, National Institute of Parasitic Diseases, Shanghai, 200025, China.
Xiu-Ping WuChinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research On Tropical Diseases, National Institute of Parasitic Diseases, Shanghai, 200025, China.
Shan LvChinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research On Tropical Diseases, National Institute of Parasitic Diseases, Shanghai, 200025, China.
Qin LiuChinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research On Tropical Diseases, National Institute of Parasitic Diseases, Shanghai, 200025, China.
Mu-Xin ChenChinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research On Tropical Diseases, National Institute of Parasitic Diseases, Shanghai, 200025, China.
Yan LuChinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research On Tropical Diseases, National Institute of Parasitic Diseases, Shanghai, 200025, China.
Zhi-Hui DouNational Center for AIDS/STD Control and Prevention, China Center for Disease Control and Prevention, Beijing, 102206, China.
Da-Wei ZhangThe People's Liberation Army 302 Hospital, Beijing, 100039, China.
Wen-Wen LvClinical Research Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Lei WangLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.
Zhen-Hui LuLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.
Ming YangLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.
Pei-Yong ZhengLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.
Yue-Lai ChenLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.
Li-Guang TianChinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research On Tropical Diseases, National Institute of Parasitic Diseases, Shanghai, 200025, China. jztlg@126.com.ORCID http://orcid.org/0000-0003-0817-6943
Xiao-Nong ZhouChinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research On Tropical Diseases, National Institute of Parasitic Diseases, Shanghai, 200025, China. zhouxn1@chinacdc.cn.
National Institute for Parasitic Diseases · CNShanghai University of Traditional Chinese Medicine · CN302 Military Hospital of China · CNChinese Center For Disease Control and Prevention · CNGansu Provincial Center for Disease Control and Prevention · CNGansu Provincial Hospital · CNNational Center for AIDS/STD Control and Prevention,China CDC · CNNational Institute for Viral Disease Control and Prevention · CNShanghai Jiao Tong University · CN

Funding

Medical Innovation Research Special Project of the Shanghai 2021 21Y11922400Medical Innovation Research Special Project of the Shanghai 2021 21Y11922500National Natural Science Foundation of China No.81473022Natural Science Foundation of Gansun Province 21JR7RA631Natural Science Foundation of Gansu Province 21JR11RA182Natural Science Foundation of Shanghai No.23ZR1463900Natural Science Foundation of Shanghai No.23ZR1464000Research Ward Construction Project of Shanghai Hospital Development Center SHDC2022CRW006Shanghai Municipal Education Commission Collaborative Innovation Cente A1-U21-205-902Shanghai Natural Science Foundation 22ZR1462100The talent fund Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine LH001.007Three-year Action Plan for Promoting Clinical Skills and Innovation Ability of Municipal Hospitals. No.SHDC2022CRS039
6 · The paper itself

Abstract

backgroundBlastocystis hominis (Bh) is zoonotic parasitic pathogen with a high prevalent globally, causing opportunistic infections and diarrhea disease. Human immunodeficiency virus (HIV) infection disrupts the immune system by depleting CD4

methodsA large-scale multi-center cross-sectional study was conducted in China from June 2020 to December 2022. The genetic presence of Bh in fecal samples was detected by real-time fluorescence quantitative polymerase chain reaction, the CD4

resultsA total of 1245 PLWH were enrolled in the study, the average age of PLWH was 43 years [interquartile range (IQR): 33, 52], with 452 (36.3%) being female, 50.4% (n = 628) had no immunosuppression (CD4

conclusionsThe study revealed that VL was a better predictor of Bh infection than CD4

Indexed as

Blastocystis InfectionsHIVAdultAntiretroviral Therapy, Highly ActiveChinaCross-Sectional StudiesFemaleHumansMaleBlastocystis hominisChinaHuman immunodeficiency virusNon-linear associationPropensity scoreRestricted cubic splineViral load

Identifiers

PMID37697423
PMCPMC10494452
OpenAlexW4386605561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.