Evidence map›Paper›PMID 37697380›Full record

SynthesisAnnals of clinical microbiology and antimicrobials2023

Tetracyclines resistance in Mycoplasma and Ureaplasma urogenital isolates derived from human: a systematic review and meta-analysis.

Xiaoyan Wen, Mojgan Sarabi Nobakht, Yue Yang, Ebrahim Kouhsari, Sara Hajilari, Matin Zafar Shakourzadeh, Khalil Azizian

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Annals of clinical microbiology and antimicrobials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Drug resistance ofFrontiers in cellular and infection microbiology · 2026
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Journal of bone and joint infection · 2024
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Xiaoyan WenUrology Department of Affiliated Hospital of Chengdu University, Chengdu, 610000, Sichuan, China. yyjakejerry@163.com.
Mojgan Sarabi NobakhtDepartment of Microbiology, Faculty of Basic Sciences, Islamic Azad University, Sirjan Branch, Sirjan, Iran.
Yue YangUrology Department of Affiliated Hospital of Chengdu University, Chengdu, 610000, Sichuan, China.
Ebrahim KouhsariLaboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Sara HajilariLaboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Matin Zafar ShakourzadehLaboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Khalil AzizianDepartment of Microbiology, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran. k.azizian86@gmail.com.
Chengdu University · CNGolestan University · IRGolestan University of Medical Sciences · IRIslamic Azad University, Sirjan Branch · IRKurdistan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUrogenital Mycoplasma infections are considered an important public health problem, owing to the presence of antibiotic resistance or decreased susceptibility, the treatment options are limited.

objectiveTherefore, this meta-analysis aimed to estimate resistance rates of genital Mycoplasmas to tetracyclines (tetracycline, doxycycline, and minocycline).

methodsWe searched the relevant published studies in PubMed, Scopus, and Embase until 3, March 2022. All statistical analyses were carried out using the statistical package R.

resultsThe 26 studies included in the analysis were performed in 15 countries. In the metadata, the proportions of tetracycline, doxycycline, and minocycline resistance in Mycoplasma and Ureaplasma urogenital isolates were reported 14.2% (95% CI 8.2-23.2%), 5% (95% CI 3-8.1%), and 11.9% (95% CI 6.3-21.5%), respectively. According to the meta-regression, the tetracycline and minocycline resistance rate decreased over time. Although, the doxycycline resistance rate increased over time. There was a statistically significant difference in the tetracyclines resistance rates between different continents/countries (P < 0.05).

conclusionThe prevalence rate and antibiotic susceptibility profiles vary geographically. Therefore, rigorous or improved antimicrobial stewardship, contact tracing, and enhanced intensive surveillance systems are necessitated for preventing the emergence and further spreading of tetracyclines resistance in genital Mycoplasmas.

Indexed as

MycoplasmaAnti-Bacterial AgentsDoxycyclineHumansMinocyclineTetracyclineAnti-Bacterial AgentsDoxycyclineMinocyclineTetracyclineAntimicrobial resistanceMeta-analysisMycoplasmaSystematic reviewTetracyclines resistanceUreaplasma

Identifiers

PMID37697380
PMCPMC10496389
OpenAlexW4386599700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.