Evidence map›Paper›PMID 37697326›Full record

ArticleSubstance abuse treatment, prevention, and policy2023

Pharmacy-based methadone treatment in the US: views of pharmacists and opioid treatment program staff.

Li-Tzy Wu, Paolo Mannelli, William S John, Alyssa Anderson, Robert P Schwartz

Open access · goldAbstract read
In one paragraph

Article in Substance abuse treatment, prevention, and policy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Delivering MOUD to the Underserved: How Can Pharmacies Really Help?Journal of studies on alcohol and drugs · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Li-Tzy WuDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA. litzy.wu@duke.edu.
Paolo MannelliDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
William S JohnCardinal Health, Dublin, OH, USA.
Alyssa AndersonIQVIA, Durham, NC, USA.
Robert P SchwartzFriends Research Institute, Inc, Baltimore, MD, USA.
Duke University · USCardinal Health (United States) · USFriends Research Institute · USIQVIA (United States) · US

Funding

Facilitating the Implementation of Interim Methadone to Increase Treatment Access: A Multi-Site Implementation TrialU01DA046910 · NIDA · FRIENDS RESEARCH INSTITUTE, INC. · PI SCHWARTZ, ROBERT P · 2018 to 2021
$4.8M
NIDA NIH HHS U01 DA046910
6 · The paper itself

Abstract

backgroundThe US federal regulations allow pharmacy administration and dispensing of methadone for opioid use disorder (PADMOUD) to increase the capability of opioid treatment programs (OTPs) in providing methadone maintenance treatment (MMT) for opioid use disorder (OUD) as part of a medication unit. However, there is a lack of research data from both pharmacy and OTP staff to inform the implementation of PADMOUD.

methodsStaff of a pharmacy (n = 8) and an OTP (n = 9) that participated in the first completed US trial on PADMOUD through electronic prescribing for methadone (parent study) were recruited to participate in this qualitative interview study to explore implementation-related factors for PADMOUD. Each interview was recorded and transcribed verbatim. NVivo was used to help identify themes of qualitative interview data. The Promoting Action on Research Implementation in Health Services (PARIHS) framework was used to guide the coding and interpretation of data.

resultsSix pharmacy staff and eight OTP staff (n = 14) completed the interview. Results based on PARIHS domains were summarized, including evidence, context, and facilitation domains. Participants perceived benefits of PADMOUD for patients, pharmacies, OTPs, and payers. PADMOUD was considered to increase access for stable patients, provide additional patient service opportunities and revenues for pharmacies/pharmacists, enhance the capability of OTPs to treat more new patients, and reduce patients' cost when receiving medication at a pharmacy relative to an OTP. Both pharmacy and OTP staff were perceived to be supportive of the implementation of PADMOUD. Pharmacy staff/pharmacists were perceived to need proper training on addiction and methadone as well as a protocol of PADMOUD to conduct PADMOUD. Facilitators include having thought leaders to guide the operation, a certification program to ensure proper training of pharmacy staff/pharmacist, having updated pharmacy service software or technology to streamline the workflow of delivering PADMOUD and inventory management, and reimbursement for pharmacists.

conclusionThis study presents the first findings on perspectives of PADMOUD from both staff of a community pharmacy and an OTP in the US. Finding on barriers and facilitators are useful data to guide the development of strategies to implement PADMOUD to help address the US opioid crisis.

Indexed as

Opioid-Related DisordersPharmaceutical ServicesPharmaciesPharmacyAnalgesics, OpioidHumansMethadonePharmacistsPharmacy AdministrationAnalgesics, OpioidMethadoneCommunity pharmacyMethadone maintenance treatmentMethadone medication unitMethadone prescribingOpioid treatment programOpioid use disorder

Identifiers

PMID37697326
PMCPMC10496162
OpenAlexW4386602547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.