Evidence map›Paper›PMID 37696949›Full record

ArticleNature cell biology2023

Widespread 8-oxoguanine modifications of miRNA seeds differentially regulate redox-dependent cancer development.

Sangkyeong Eom, Jongjin Peak, Jongyeun Park, Seung Hyun Ahn, You Kyung Cho, Yeahji Jeong, Hye-Sook Lee, Jung Lee, Elizaveta Ignatova, Sung Eun Lee and 9 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature cell biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 40 citations in OpenAlex.

  1. Dysregulated mScience advances · 2026
    Article
  2. An Integrated DNA Nanoprobe for Intranuclear Imaging and In Situ Profiling of OGG1 Activity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. A BBB-permeable βScience advances · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. o8G-modified circKIAA1797 promotes lung cancer development by inhibiting cuproptosis.Journal of experimental & clinical cancer research : CR · 2025
    Article
  19. The biogenesis and regulation of animal microRNAs.Nature reviews. Molecular cell biology · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Sangkyeong Eom *Department of Life Sciences, Korea University, Seoul, Korea.
Jongjin Peak *Department of Life Sciences, Korea University, Seoul, Korea.ORCID http://orcid.org/0000-0002-7099-1888
Jongyeun Park *Department of Life Sciences, Korea University, Seoul, Korea.ORCID http://orcid.org/0000-0001-7394-5361
Seung Hyun Ahn *Department of Life Sciences, Korea University, Seoul, Korea.
You Kyung ChoDepartment of Life Sciences, Korea University, Seoul, Korea.
Yeahji JeongDepartment of Life Sciences, Korea University, Seoul, Korea.ORCID http://orcid.org/0000-0003-0464-1422
Hye-Sook LeeDepartment of Life Sciences, Korea University, Seoul, Korea.
Jung LeeKU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, Korea.ORCID http://orcid.org/0000-0003-1177-7117
Elizaveta IgnatovaDepartment of Life Sciences, Korea University, Seoul, Korea.
Sung Eun LeeDepartment of Life Sciences, Korea University, Seoul, Korea.
Yunji HongDepartment of Life Sciences, Korea University, Seoul, Korea.
Dowoon GuDepartment of Life Sciences, Korea University, Seoul, Korea.ORCID http://orcid.org/0000-0002-8551-7863
Geun-Woo D KimDepartment of Life Sciences, Korea University, Seoul, Korea.
Dong Chan LeeDepartment of Life Sciences, Korea University, Seoul, Korea.
Ja Young HahmDepartment of Life Sciences, Korea University, Seoul, Korea.ORCID http://orcid.org/0000-0001-9989-9113
Jaemin JeongDepartment of Surgery, Hanyang University College of Medicine, Seoul, Korea.
Dongho ChoiDepartment of Surgery, Hanyang University College of Medicine, Seoul, Korea.
Eun-Sook JangDepartment of Life Sciences, Korea University, Seoul, Korea.
Sung Wook ChiDepartment of Life Sciences, Korea University, Seoul, Korea. chi13@korea.ac.kr.ORCID http://orcid.org/0000-0002-8035-8242
Korea University · KRHanyang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress contributes to tumourigenesis by altering gene expression. One accompanying modification, 8-oxoguanine (o

Indexed as

Carcinoma, HepatocellularGliomaLiver NeoplasmsMicroRNAsAnimalsCarcinogenesisGuanineMiceOxidation-Reduction8-hydroxyguanineGuanineMicroRNAs

Identifiers

PMID37696949
OpenAlexW4386600193

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.