Evidence map›Paper›PMID 37696851›Full record

ArticleScientific data2023

DISCOVER-EEG: an open, fully automated EEG pipeline for biomarker discovery in clinical neuroscience.

Cristina Gil Ávila, Felix S Bott, Laura Tiemann, Vanessa D Hohn, Elisabeth S May, Moritz M Nickel, Paul Theo Zebhauser, Joachim Gross, Markus Ploner

Open access · goldAbstract read
In one paragraph

Article in Scientific data, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

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  19. Using Electroencephalography to Advance Mindfulness Science: A Survey of Emerging Methods and Approaches.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Cristina Gil ÁvilaDepartment of Neurology, TUM School of Medicine, Technical University of Munich, München, Germany.ORCID http://orcid.org/0000-0003-3789-0644
Felix S BottDepartment of Neurology, TUM School of Medicine, Technical University of Munich, München, Germany.
Laura TiemannDepartment of Neurology, TUM School of Medicine, Technical University of Munich, München, Germany.ORCID http://orcid.org/0000-0002-5261-5459
Vanessa D HohnDepartment of Neurology, TUM School of Medicine, Technical University of Munich, München, Germany.
Elisabeth S MayDepartment of Neurology, TUM School of Medicine, Technical University of Munich, München, Germany.ORCID http://orcid.org/0000-0002-8558-6447
Moritz M NickelDepartment of Neurology, TUM School of Medicine, Technical University of Munich, München, Germany.ORCID http://orcid.org/0000-0001-6614-243X
Paul Theo ZebhauserDepartment of Neurology, TUM School of Medicine, Technical University of Munich, München, Germany.
Joachim GrossInstitute for Biomagnetism and Biosignalanalysis, University of Münster, Münster, Germany.
Markus PlonerDepartment of Neurology, TUM School of Medicine, Technical University of Munich, München, Germany. markus.ploner@tum.de.ORCID http://orcid.org/0000-0002-7767-7170
Technical University of Munich · DETumaini University · TZUniversity of Münster · DE

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) PL321/14-1Technical University of Munich | Fakultät für Medizin, Technische Universität München (Faculty of Medicine, Technische Universität München) KKF
6 · The paper itself

Abstract

Biomarker discovery in neurological and psychiatric disorders critically depends on reproducible and transparent methods applied to large-scale datasets. Electroencephalography (EEG) is a promising tool for identifying biomarkers. However, recording, preprocessing, and analysis of EEG data is time-consuming and researcher-dependent. Therefore, we developed DISCOVER-EEG, an open and fully automated pipeline that enables easy and fast preprocessing, analysis, and visualization of resting state EEG data. Data in the Brain Imaging Data Structure (BIDS) standard are automatically preprocessed, and physiologically meaningful features of brain function (including oscillatory power, connectivity, and network characteristics) are extracted and visualized using two open-source and widely used Matlab toolboxes (EEGLAB and FieldTrip). We tested the pipeline in two large, openly available datasets containing EEG recordings of healthy participants and patients with a psychiatric condition. Additionally, we performed an exploratory analysis that could inspire the development of biomarkers for healthy aging. Thus, the DISCOVER-EEG pipeline facilitates the aggregation, reuse, and analysis of large EEG datasets, promoting open and reproducible research on brain function.

Indexed as

Biomedical ResearchHealthy AgingBrainElectroencephalographyHealthy VolunteersHumans

Identifiers

PMID37696851
PMCPMC10495446
OpenAlexW4386602382

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.