ReviewCold Spring Harbor perspectives in biology2023
Mechanisms of Intrinsic Postzygotic Isolation: From Traditional Genic and Chromosomal Views to Genomic and Epigenetic Perspectives.
Review in Cold Spring Harbor perspectives in biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Rapid genome-wide purging following tsunami-induced hybridization in a stickleback population.Nature ecology & evolution · 2026Article
- Repeat offenders: Satellite DNA sequence variation drives heterochromatin instability.Science advances · 2026Review
- The Evolution of Reproductive Isolation Beyond a Strong First Barrier in Speciation Between Micro-Allopatric Host Races of a Phytophagous Ladybird Beetle,Ecology and evolution · 2026Article
- Beyond the Prdm9 model: independent evolution of hybrid male sterility in house mice.Heredity · 2026Article
- Article
- How population subsampling to concentrate selection effects can help to find epistatic interactions of transmission ratio distortion.Heredity · 2026Article
- The molecular evolutionary basis of species formation revisited.Trends in genetics : TIG · 2025Review
- 3D Genome Constrains Breakpoints of Inversions That Can Act as Barriers to Gene Flow in the Stickleback.Molecular ecology · 2025Article
- A species interaction kick-starts ecological speciation in allopatry.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Mouse X-linked microRNA cluster regulates the meiotic checkpoint andProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Hybridization and gene expression: Beyond differentially expressed genes.Molecular ecology · 2025Review
- Pervasive gene flow despite strong and varied reproductive barriers in swordtails.Nature ecology & evolution · 2025Article
- United by conflict: Convergent signatures of parental conflict in angiosperms and placental mammals.The Journal of heredity · 2024Review
- Synthesis and Scope of the Role of Postmating Prezygotic Isolation in Speciation.Cold Spring Harbor perspectives in biology · 2024Review
- The Ecology of Hybrid Incompatibilities.Cold Spring Harbor perspectives in biology · 2024Review
- Regulatory and evolutionary impact of DNA methylation in two songbird species and their naturally occurring FBMC biology · 2024Article
- Pervasive gene flow despite strong and varied reproductive barriers in swordtails.bioRxiv : the preprint server for biology · 2024Article
- A cyclical switch of gametogenic pathways in hybrids depends on the ploidy level.Communications biology · 2024Article
- How Important Is Sexual Isolation to Speciation?Cold Spring Harbor perspectives in biology · 2024Review
- Structural Variants and Speciation: Multiple Processes at Play.Cold Spring Harbor perspectives in biology · 2024Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intrinsic postzygotic isolation typically appears as reduced viability or fertility of interspecific hybrids caused by genetic incompatibilities between diverged parental genomes. Dobzhansky-Muller interactions among individual genes, and chromosomal rearrangements causing problems with chromosome synapsis and recombination in meiosis, have both long been considered as major mechanisms behind intrinsic postzygotic isolation. Recent research has, however, suggested that the genetic basis of intrinsic postzygotic isolation can be more complex and involves, for example, overall divergence of the DNA sequence or epigenetic changes. Here, we review the mechanisms of intrinsic postzygotic isolation from genic, chromosomal, genomic, and epigenetic perspectives across diverse taxa. We provide empirical evidence for these mechanisms, discuss their importance in the speciation process, and highlight questions that remain unanswered.
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