Evidence map›Paper›PMID 37696224›Full record

ReviewAnimal reproduction science2023

Role of the placenta in developmental programming: Observations from models using large animals.

L P Reynolds, C R Dahlen, A K Ward, M S Crouse, P P Borowicz, B J Davila-Ruiz, C Kanjanaruch, K A Bochantin, K J McLean, K L McCarthy and 4 more

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Animal reproduction science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
20.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Placental adaptation to maternal environment in domestic animals.The Journal of reproduction and development · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

L P ReynoldsCenter for Nutrition and Pregnancy, and Department of Animal Sciences, North Dakota State University, Fargo, ND 58108-6050, USA. Electronic address: larry.reynolds@ndsu.edu.
C R DahlenCenter for Nutrition and Pregnancy, and Department of Animal Sciences, North Dakota State University, Fargo, ND 58108-6050, USA.
A K WardCenter for Nutrition and Pregnancy, and Department of Animal Sciences, North Dakota State University, Fargo, ND 58108-6050, USA.
M S CrouseNutrition, Growth, and Physiology Research Unit, USDA/Agricultural Research Service, U.S. Meat Animal Research Center, Clay Center, NE 68933-0166, USA.
P P BorowiczCenter for Nutrition and Pregnancy, and Department of Animal Sciences, North Dakota State University, Fargo, ND 58108-6050, USA.
B J Davila-RuizCenter for Nutrition and Pregnancy, and Department of Animal Sciences, North Dakota State University, Fargo, ND 58108-6050, USA.
C KanjanaruchCenter for Nutrition and Pregnancy, and Department of Animal Sciences, North Dakota State University, Fargo, ND 58108-6050, USA.
K A BochantinCenter for Nutrition and Pregnancy, and Department of Animal Sciences, North Dakota State University, Fargo, ND 58108-6050, USA.
K J McLeanDepartment of Animal Science, University of Tennessee Knoxville, Knoxville, TN 37996-4500, USA.
K L McCarthyDepartment of Animal Science, University of Nebraska Lincoln, Lincoln, NE 68583-0908, USA.
A C B MenezesDepartment of Animal Science, South Dakota State University, Brookings, SD 57006, USA.
W J S DinizDepartment of Animal Sciences, Auburn University, Auburn, AL 36832, USA.
R A CushmanNutrition, Growth, and Physiology Research Unit, USDA/Agricultural Research Service, U.S. Meat Animal Research Center, Clay Center, NE 68933-0166, USA.
J S CatonCenter for Nutrition and Pregnancy, and Department of Animal Sciences, North Dakota State University, Fargo, ND 58108-6050, USA.
North Dakota State University · USRoman L. Hruska U.S. Meat Animal Research Center · USAuburn University · USSouth Dakota State University · USUniversity of Nebraska–Lincoln · USUniversity of Tennessee at Knoxville · US

Funding

Nutrition, Fetal Growth, and Placental AngiogenesisR01HD045784 · NICHD · NORTH DAKOTA STATE UNIVERSITY · PI REYNOLDS, LAWRENCE P · 2005 to 2010
$1.7M
THE MAJOR ANGIOGENIC FACTORS IN PLACENTAL ANGIOGENESIS.R01HL064141 · NHLBI · NORTH DAKOTA STATE UNIVERSITY · PI REYNOLDS, LAWRENCE P · 2001 to 2004
$589k
NHLBI NIH HHS R01 HL064141NICHD NIH HHS R01 HD045784
6 · The paper itself

Abstract

Developmental programming, which proposes that "insults" or "stressors" during intrauterine or postnatal development can have not only immediate but also long-term consequences for healthy and productivity, has emerged as a major biological principle, and based on studies in many animal species also seems to be a universal phenomenon. In eutherians, the placenta appears to be programmed during its development, which has consequences for fetal growth and development throughout pregnancy, and likewise has long-term consequences for postnatal development, leading to programming of organ function of the offspring even into adulthood. This review summarizes our current understanding of the placenta's role in developmental programming, the mechanisms involved, and the challenges remaining.

Indexed as

Fetal DevelopmentPlacentaAnimalsFemalePregnancyBlood flowDevelopmental programmingFetal growthFunctionPlacentaVascularity

Identifiers

PMID37696224
PMCPMC10591737
OpenAlexW4386295770

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.