Evidence map›Paper›PMID 37695913›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Autism- and epilepsy-associated

Muhaned S Mohamed, Eric Klann

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. The regulation, function and disease relevance of cytoplasmic tRNAs.Nature reviews. Molecular cell biology · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Muhaned S MohamedCenter for Neural Science, New York University, New York, NY 10003.ORCID 0000-0002-4388-8957
Eric KlannCenter for Neural Science, New York University, New York, NY 10003.ORCID 0000-0001-7379-6802
NYU Langone Health · US

Funding

Translational Control in Memory and Brain DisordersR35NS122316 · NINDS · NEW YORK UNIVERSITY · PI Eric Klann · 2021 to 2026
$6.5M
Dysregulated Ribosomal Protein Synthesis in Amyloid and Tau Mouse ModelsR21NS121786 · NINDS · NEW YORK UNIVERSITY · PI KLANN, ERIC · 2021 to 2021
$436k
Functional Characterization of ASD-Associated EEF1A2 Mutations in Human NeuronsF30HD103360 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MOHAMED, MUHANED · 2020 to 2024
$226k
NICHD NIH HHS F30 HD103360NINDS NIH HHS R21 NS121786NINDS NIH HHS R35 NS122316
6 · The paper itself

Abstract

Protein synthesis is a fundamental cellular process in neurons that is essential for synaptic plasticity and memory consolidation. Here, we describe our investigations of a neuron- and muscle-specific translation factor,

Indexed as

Autistic DisorderEpilepsyPeptide Elongation Factor 1ActinsAnimalsHEK293 CellsHumansMiceMutationActinsEEF1A2 protein, humanEef1a2 protein, mousePeptide Elongation Factor 1autismepilepsyneurodevelopmentprotein synthesistranslation

Identifiers

PMID37695913
PMCPMC10515156
OpenAlexW4386590239

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.