ArticleAmerican journal of respiratory and critical care medicine2023
Inflammatory Activity of Epithelial Stem Cell Variants from Cystic Fibrosis Lungs Is Not Resolved by CFTR Modulators.
Erratum issuedOpen access · hybridAbstract read
In one paragraph
Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- Progenitor Resilience and the Early Onset of Chronic Lung Diseases: NHLBI workshop report.American journal of respiratory cell and molecular biology · 2026Article
- Transcriptomic and functional responses of the cystic fibrosis airway epithelium to CFTR modulator therapy.JCI insight · 2025Article
- Human bronchial basal cells are a community of variants.iScience · 2025Article
- TGF-β induces excessive pulmonary IL-6 secretion in cystic fibrosis via PI3K.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- Wound repair and immune function in theFrontiers in cellular and infection microbiology · 2025Review
- Lung stem cells and respiratory epithelial chimerism in transplantation.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- Autologous transplantation of lung progenitor cells comes into reality for bronchiectasis.Cell reports. Medicine · 2024Article
- Erratum: Inflammatory Activity of Epithelial Stem Cell Variants from Cystic Fibrosis Lungs Is Not Resolved by CFTR Modulators.American journal of respiratory and critical care medicine · 2024Article
- Epithelial responses to CFTR modulators are improved by inflammatory cytokines and impaired by antiinflammatory drugs.JCI insight · 2024Article
- Pharmacological Improvement of Cystic Fibrosis Transmembrane Conductance Regulator Function Rescues Airway Epithelial Homeostasis and Host Defense in Children with Cystic Fibrosis.American journal of respiratory and critical care medicine · 2024Article
- Article
- Cystic Fibrosis Airways: Does Disease Stem from Faulty Stem Cells?American journal of respiratory and critical care medicine · 2023Article
- Phoenix from the Ashes: Celebrating the 2023 North American Cystic Fibrosis Conference.American journal of respiratory and critical care medicine · 2023Article
Corrections and comments
- Commented on by
- Commented on by
- Erratum issued
Authors and funding
22 authors at 10 institutions in 1 country.
Shan WangDepartment of Biology and Biochemistry, University of Houston, Houston, Texas.ORCID 0000-0002-9035-2290
Suchan NiroulaDepartment of Biology and Biochemistry, University of Houston, Houston, Texas.
Ashley HoffmanDepartment of Biology and Biochemistry, University of Houston, Houston, Texas.
Melika KhorramiDepartment of Biology and Biochemistry, University of Houston, Houston, Texas.
Melina KhorramiDepartment of Biology and Biochemistry, University of Houston, Houston, Texas.
Feng YuanDepartment of Anatomy and Cell Biology.ORCID 0000-0002-5210-8510
Grace N GasserDepartment of Anatomy and Cell Biology.
Soon ChoiDepartment of Anatomy and Cell Biology.
Bovey LiuDepartment of Biology and Biochemistry, University of Houston, Houston, Texas.
Justin LiAccuraScience, Johnston, Iowa.
Mark L MeterskyCenter for Bronchiectasis Care, Pulmonary, Critical Care, and Sleep Medicine, University of Connecticut Health Center, Farmington, Connecticut.
Matthew VincentTract Bio, Houston, Texas.
Christopher P CrumWomen's and Perinatal Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Richard C BoucherCystic Fibrosis and Pulmonary Research and Treatment Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Harry Karmouty-QuintanaDepartment of Biochemistry and Molecular Biology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas.ORCID 0000-0003-4753-9823
Howard J HuangDepartment of Medicine, Houston Methodist Hospital, Houston, Texas; and.
Ajay SheshadriDepartment of Pulmonary Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas.
Burton F DickeyDepartment of Pulmonary Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-4780-1847
Kalpaj R ParekhDepartment of Anatomy and Cell Biology.
John F EngelhardtDepartment of Anatomy and Cell Biology.
Frank D McKeonDepartment of Biology and Biochemistry, University of Houston, Houston, Texas.ORCID 0000-0002-7747-9983
Wa XianDepartment of Biology and Biochemistry, University of Houston, Houston, Texas.
University of Houston · USThe University of Texas MD Anderson Cancer Center · USBiotex (United States) · USBrigham and Women's Hospital · USConnecticut Center for Primary Care · USJohnston Community College · USMethodist Hospital · USThe University of Texas Health Science Center at Houston · USUniversity of Iowa · USUniversity of North Carolina at Chapel Hill · US
Funding
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Jong Sung Kim · 1990 to 2026
$40.5MThe Biophysics of Mucus Hydration and Adhesion/CohesionP01HL108808 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOUCHER, RICHARD CHARLES · 2012 to 2021
$23.9MCommon Stem Cell of Origin for Junctional and Gastric AdenocarcinomaR01CA272906 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jaffer A. Ajani, FRANK D. MCKEON · 2022 to 2026
$4.6MPathogenesis of Airway Stem Cell Abnormalities in Obliterative BronchiolitisR01HL136370 · NHLBI · UNIVERSITY OF IOWA · PI Kalpaj Rajnikant Parekh, Wa Xian · 2019 to 2026
$4.2MControlling the core airway mucin secretion machinery to prevent pathophysiologyR01HL129795 · NHLBI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DICKEY, BURTON F · 2015 to 2023
$3.8MMultiscale Biochemical/Biophysical Integration of Pulmonary Mucus TransportR01HL136961 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOUCHER, RICHARD CHARLES · 2017 to 2020
$3.2MBiology of Submucosal Gland Stem Cells in the AirwayR01HL165404 · NHLBI · UNIVERSITY OF IOWA · PI ENGELHARDT, JOHN F · 2022 to 2025
$2.9MPro-Inflammatory Stem Cell Variants in Cystic FibrosisR01HL149678 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MCKEON, FRANK D. · 2022 to 2025
$2.7MPathogenic Heterogeneity in Mucosal Stem Cells in Pediatric Crohn's DiseaseR01DK115445 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI XIAN, WA · 2018 to 2021
$2.6M3'UTR Shortening In Pulmonary Vascular DiseaseR01HL138510 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KARMOUTY-QUINTANA, HARRY · 2017 to 2021
$2.3MClonal Reconstruction and Targeting of the Correa SequenceR01CA241600 · NCI · UNIVERSITY OF HOUSTON · PI MCKEON, FRANK D. · 2019 to 2023
$2.3MNew vertebrate model organism cDNA librariesR24RR015088 · NCRR · UNIVERSITY OF CALIFORNIA IRVINE · PI BLUMBERG, BRUCE · 2001 to 2003
$1.1MNCI NIH HHS R01 CA241600NCI NIH HHS R01 CA272906NCI NIH HHS U24 CA228550NCRR NIH HHS R24 RR015088NHLBI NIH HHS P01 HL108808NHLBI NIH HHS R01 HL129795NHLBI NIH HHS R01 HL136370NHLBI NIH HHS R01 HL136961NHLBI NIH HHS R01 HL138510NHLBI NIH HHS R01 HL149678NHLBI NIH HHS R01 HL165404NIDDK NIH HHS R01 DK115445
Abstract
PubMed holds no abstract for this paper.
Indexed as
Cystic FibrosisPulmonary Disease, Chronic ObstructiveAnimalsChild, PreschoolCystic Fibrosis Transmembrane Conductance RegulatorHumansInflammationLungMiceCFTR protein, humanCystic Fibrosis Transmembrane Conductance RegulatorCFTR modulatorscystic fibrosislung inflammationlung stem cellsneutrophils.
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.