Evidence map›Paper›PMID 37695796›Full record

ArticlePLoS computational biology2023

Testing predictive coding theories of autism spectrum disorder using models of active inference.

Tom Arthur, Sam Vine, Gavin Buckingham, Mark Brosnan, Mark Wilson, David Harris

Abstract read
In one paragraph

Article in PLoS computational biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Reduced Dissociation Between Perception and Action in Autistic Individuals.Journal of autism and developmental disorders · 2026
    Article
  4. Hidden State Inference or Continuous Belief Updating during a Dynamic Visuomotor Skill.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tom ArthurSchool of Public Health and Sport Sciences, Medical School, University of Exeter, Exeter, United Kingdom.
Sam VineSchool of Public Health and Sport Sciences, Medical School, University of Exeter, Exeter, United Kingdom.
Gavin BuckinghamSchool of Public Health and Sport Sciences, Medical School, University of Exeter, Exeter, United Kingdom.
Mark BrosnanCentre for Applied Autism Research, Department of Psychology, University of Bath, Bath, United Kingdom.
Mark WilsonSchool of Public Health and Sport Sciences, Medical School, University of Exeter, Exeter, United Kingdom.
David HarrisSchool of Public Health and Sport Sciences, Medical School, University of Exeter, Exeter, United Kingdom.ORCID 0000-0003-3880-3856

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several competing neuro-computational theories of autism have emerged from predictive coding models of the brain. To disentangle their subtly different predictions about the nature of atypicalities in autistic perception, we performed computational modelling of two sensorimotor tasks: the predictive use of manual gripping forces during object lifting and anticipatory eye movements during a naturalistic interception task. In contrast to some accounts, we found no evidence of chronic atypicalities in the use of priors or weighting of sensory information during object lifting. Differences in prior beliefs, rates of belief updating, and the precision weighting of prediction errors were, however, observed for anticipatory eye movements. Most notably, we observed autism-related difficulties in flexibly adapting learning rates in response to environmental change (i.e., volatility). These findings suggest that atypical encoding of precision and context-sensitive adjustments provide a better explanation of autistic perception than generic attenuation of priors or persistently high precision prediction errors. Our results did not, however, support previous suggestions that autistic people perceive their environment to be persistently volatile.

Indexed as

Autism Spectrum DisorderAutistic DisorderBrainEye MovementsHumansLearning

Identifiers

PMID37695796
PMCPMC10529610

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.