Evidence map›Paper›PMID 37695769›Full record

ReviewPLOS digital health2023

Heart murmur detection from phonocardiogram recordings: The George B. Moody PhysioNet Challenge 2022.

Matthew A Reyna, Yashar Kiarashi, Andoni Elola, Jorge Oliveira, Francesco Renna, Annie Gu, Erick A Perez Alday, Nadi Sadr, Ashish Sharma, Jacques Kpodonu and 5 more

Abstract readReview
In one paragraph

Review in PLOS digital health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Beyond Heart Murmur Detection: Automatic Murmur Grading From Phonocardiogram.IEEE journal of biomedical and health informatics · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Matthew A ReynaDepartment of Biomedical Informatics, Emory University, Atlanta, Georgia, United States of America.ORCID https://orcid.org/0000-0003-4688-7965
Yashar KiarashiDepartment of Biomedical Informatics, Emory University, Atlanta, Georgia, United States of America.
Andoni ElolaDepartment of Electronic Technology, University of the Basque Country UPV/EHU, Eibar, Spain.
Jorge OliveiraREMIT, Universidade Portucalense, Porto, Portugal.
Francesco RennaINESC TEC, Faculdade de Ciências, Universidade do Porto, Porto, Portugal.
Annie GuDepartment of Biomedical Informatics, Emory University, Atlanta, Georgia, United States of America.
Erick A Perez AldayDepartment of Biomedical Informatics, Emory University, Atlanta, Georgia, United States of America.
Nadi SadrDepartment of Biomedical Informatics, Emory University, Atlanta, Georgia, United States of America.
Ashish SharmaDepartment of Biomedical Informatics, Emory University, Atlanta, Georgia, United States of America.
Jacques KpodonuDivision of Cardiac Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America.
Sandra MattosUnidade de Cardiologia e Medicina Fetal, Real Hospital Português, Recife, Brazil.
Miguel T CoimbraINESC TEC, Faculdade de Ciências, Universidade do Porto, Porto, Portugal.ORCID https://orcid.org/0000-0001-7501-6523
Reza SameniDepartment of Biomedical Informatics, Emory University, Atlanta, Georgia, United States of America.ORCID https://orcid.org/0000-0003-4913-6825
Ali Bahrami RadDepartment of Biomedical Informatics, Emory University, Atlanta, Georgia, United States of America.
Gari D CliffordDepartment of Biomedical Informatics, Emory University, Atlanta, Georgia, United States of America.

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Research Resource for Complex Physiologic SignalsR01EB030362 · NIBIB · BETH ISRAEL DEACONESS MEDICAL CENTER · PI GOLDBERGER, ARY LOUIS · 2020 to 2025
$5.8M
Research Resource for Complex Physiologic SignalsR01GM104987 · NIGMS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI GOLDBERGER, ARY LOUIS, MARK, ROGER GREENWOOD · 2012 to 2019
$5.8M
NCATS NIH HHS UL1 TR002378NIBIB NIH HHS R01 EB030362NIGMS NIH HHS R01 GM104987
6 · The paper itself

Abstract

Cardiac auscultation is an accessible diagnostic screening tool that can help to identify patients with heart murmurs, who may need follow-up diagnostic screening and treatment for abnormal cardiac function. However, experts are needed to interpret the heart sounds, limiting the accessibility of cardiac auscultation in resource-constrained environments. Therefore, the George B. Moody PhysioNet Challenge 2022 invited teams to develop algorithmic approaches for detecting heart murmurs and abnormal cardiac function from phonocardiogram (PCG) recordings of heart sounds. For the Challenge, we sourced 5272 PCG recordings from 1452 primarily pediatric patients in rural Brazil, and we invited teams to implement diagnostic screening algorithms for detecting heart murmurs and abnormal cardiac function from the recordings. We required the participants to submit the complete training and inference code for their algorithms, improving the transparency, reproducibility, and utility of their work. We also devised an evaluation metric that considered the costs of screening, diagnosis, misdiagnosis, and treatment, allowing us to investigate the benefits of algorithmic diagnostic screening and facilitate the development of more clinically relevant algorithms. We received 779 algorithms from 87 teams during the Challenge, resulting in 53 working codebases for detecting heart murmurs and abnormal cardiac function from PCG recordings. These algorithms represent a diversity of approaches from both academia and industry, including methods that use more traditional machine learning techniques with engineered clinical and statistical features as well as methods that rely primarily on deep learning models to discover informative features. The use of heart sound recordings for identifying heart murmurs and abnormal cardiac function allowed us to explore the potential of algorithmic approaches for providing more accessible diagnostic screening in resource-constrained environments. The submission of working, open-source algorithms and the use of novel evaluation metrics supported the reproducibility, generalizability, and clinical relevance of the research from the Challenge.

Identifiers

PMID37695769
PMCPMC10495026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.