Evidence map›Paper›PMID 37695741›Full record

ArticleBlood advances2023

Intensive hydroxyurea dosing in very young children with sickle cell anemia.

Winfred C Wang, R Clark Brown, Melissa A McNaull, Zora R Rogers, Martha Barton, Meghna R Dua, Jane S Hankins, Jeffrey Gossett, Julie Richardson, Jerlym S Porter and 2 more

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Winfred C WangDepartment of Hematology, St. Jude Children's Research Hospital, Memphis, TN.
R Clark BrownDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA.
Melissa A McNaullDepartment of Pediatrics, University of Mississippi Medical Center, Jackson, MS.
Zora R RogersDepartment of Pediatric Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, TX.
Martha BartonDepartment of Hematology, St. Jude Children's Research Hospital, Memphis, TN.ORCID 0009-0003-1625-8284
Meghna R DuaDepartment of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN.
Jane S HankinsDepartment of Hematology, St. Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0003-4439-7321
Jeffrey GossettDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0002-0260-0048
Julie RichardsonDepartment of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN.
Jerlym S PorterDepartment of Psychology, St. Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0003-0173-6522
Guolian KangDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN.
Jeremie H EsteppDepartment of Hematology, St. Jude Children's Research Hospital, Memphis, TN.
St. Jude Children's Research Hospital · USEmory University · USThe University of Texas Southwestern Medical Center · USUniversity of Mississippi Medical Center · US

Funding

Hydroxyurea Management in Kids: Intensive versus Stable Dosage Strategies (HUGKISS)R34HL127162 · NHLBI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI ESTEPP, JEREMIE · 2016 to 2018
$744k
NHLBI NIH HHS R34 HL127162
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anemia, Sickle CellHydroxyureaAntisickling AgentsChildChild, PreschoolHumansAntisickling AgentsHydroxyurea

Identifiers

PMID37695741
PMCPMC10685164
OpenAlexW4386599949

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.