Evidence map›Paper›PMID 37695458›Full record

ArticleAnnals of surgical oncology2023

Growing Deficit in New Cancer Diagnoses 2 Years Into the COVID-19 Pandemic: A National Multicenter Study.

Brian R Englum, Shalini Sahoo, Minerva Mayorga-Carlin, Hilary Hayssen, Tariq Siddiqui, Douglas J Turner, John D Sorkin, Brajesh K Lal

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Annals of surgical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Disparities in Colorectal Cancer Screening.Annals of surgical oncology · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Brian R EnglumDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Shalini SahooDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Minerva Mayorga-CarlinDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Hilary HayssenDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Tariq SiddiquiDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Douglas J TurnerDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
John D SorkinGeriatrics Research, Education, and Clinical Center, Veterans Affairs Medical Center, Baltimore, MD, USA.
Brajesh K LalDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA. blal@som.umaryland.edu.
University of Maryland, Baltimore · USVeterans Health Administration · US

Funding

CREST-2 Clinical Coordinating CenterU01NS080168 · NINDS · MAYO CLINIC JACKSONVILLE · PI Thomas G Brott, JAMES F MESCHIA · 2014 to 2026
$56.3M
University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D · 2005 to 2019
$17.3M
Healthy Aging Neighborhoods of Diversity Across LifespanZ01AG000513 · NIA · NATIONAL INSTITUTE ON AGING · PI EVANS, MICHELE K · 2001 to 2008
$6.8M
Carotid Revascularization and Medical Management for Asymptomatic CarotidStenosis Trial - Hemodynamics (CREST-H)R01NS097876 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI RONALD M LAZAR, DAVID SIGMUND LIEBESKIND · 2017 to 2026
$6.4M
Disparities in Cancer Outcomes from the COVID-19 PandemicR21MD018665 · NIMHD · UNIVERSITY OF MARYLAND BALTIMORE · PI ENGLUM, BRIAN ROBERT · 2023 to 2024
$425k
CSRD VA I01 CX001621Intramural NIH HHS Z01 AG000513NIA NIH HHS AG000513NIA NIH HHS AG028747NIA NIH HHS P30 AG028747NIDDK NIH HHS DK072488NIDDK NIH HHS P30 DK072488NIMHD NIH HHS MD018665NIMHD NIH HHS R21 MD018665NINDS NIH HHS NS080168NINDS NIH HHS NS097876NINDS NIH HHS R01 NS097876NINDS NIH HHS U01 NS080168RRD VA I01 RX000995
6 · The paper itself

Abstract

backgroundLarge decreases in cancer diagnoses were seen early in the COVID-19 pandemic. However, the evolution of these deficits since the end of 2020 and the advent of widespread vaccination is unknown.

methodsThis study examined data from the Veterans Health Administration (VA) from 1 January 2018 through 28 February 2022 and identified patients with screening or diagnostic procedures or new cancer diagnoses for the four most common cancers in the VA health system: prostate, lung, colorectal, and bladder cancers. Monthly procedures and new diagnoses were calculated, and the pre-COVID era (January 2018 to February 2020) was compared with the COVID era (March 2020 to February 2022).

resultsThe study identified 2.5 million patients who underwent a diagnostic or screening procedure related to the four cancers. A new cancer was diagnosed for 317,833 patients. During the first 2 years of the pandemic, VA medical centers performed 13,022 fewer prostate biopsies, 32,348 fewer cystoscopies, and 200,710 fewer colonoscopies than in 2018-2019. These persistent deficits added a cumulative deficit of nearly 19,000 undiagnosed prostate cancers and 3300 to 3700 undiagnosed cancers each for lung, colon, and bladder. Decreased diagnostic and screening procedures correlated with decreased new diagnoses of cancer, particularly cancer of the prostate (R = 0.44) and bladder (R = 0.27).

conclusionDisruptions in new diagnoses of four common cancers (prostate, lung, bladder, and colorectal) seen early in the COVID-19 pandemic have persisted for 2 years. Although reductions improved from the early pandemic, new reductions during the Delta and Omicron waves demonstrate the continued impact of the COVID-19 pandemic on cancer care.

Indexed as

Colorectal NeoplasmsCOVID-19Prostatic NeoplasmsHumansMalePandemicsUrinary Bladder

Identifiers

PMID37695458
PMCPMC10939008
OpenAlexW4386592176

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.