Evidence map›Paper›PMID 37694274›Full record

ArticleCurrent opinion in colloid & interface science2023

Advances in Nitric Oxide-Releasing Hydrogels for Biomedical Applications.

Lori M Estes Bright, Yi Wu, Elizabeth J Brisbois, Hitesh Handa

Open access · greenAbstract read
In one paragraph

Article in Current opinion in colloid & interface science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. 3D Bioprinting of Blood Vessel Model for Improving Wound Healing.International journal of molecular sciences · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. ACS applied materials & interfaces · 2024
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lori M Estes BrightSchool of Chemical, Materials, and Biomedical Engineering, College of Engineering, University of Georgia, Athens, GA, USA.
Yi WuSchool of Chemical, Materials, and Biomedical Engineering, College of Engineering, University of Georgia, Athens, GA, USA.
Elizabeth J BrisboisSchool of Chemical, Materials, and Biomedical Engineering, College of Engineering, University of Georgia, Athens, GA, USA.
Hitesh HandaSchool of Chemical, Materials, and Biomedical Engineering, College of Engineering, University of Georgia, Athens, GA, USA.
University of Georgia · US

Funding

Engineering nitric oxide releasing polymer with immobilized thrombin inhibitor for blood contacting applicationsR01HL134899 · NHLBI · UNIVERSITY OF GEORGIA · PI HANDA, HITESH · 2017 to 2025
$3.0M
Heparin-free extracorporeal circulation via combined nitric oxide releasing/generating surfacesR01HL157587 · NHLBI · UNIVERSITY OF GEORGIA · PI BRISBOIS, ELIZABETH JOY · 2021 to 2024
$1.5M
NHLBI NIH HHS R01 HL134899NHLBI NIH HHS R01 HL157587
6 · The paper itself

Abstract

Hydrogels provide a plethora of advantages to biomedical treatments due to their highly hydrophilic nature and tissue-like mechanical properties. Additionally, the numerous and widespread endogenous roles of nitric oxide have led to an eruption in research developing biomimetic solutions to the many challenges the biomedical world faces. Though many design factors and fabrication details must be considered, utilizing hydrogels as nitric oxide delivery vehicles provides promising materials in several applications. Such applications include cardiovascular therapy, vasodilation and angiogenesis, antimicrobial treatments, wound dressings, and stem cell research. Herein, a recent update on the progress of NO-releasing hydrogels is presented in depth. In addition, considerations for the design and fabrication of hydrogels and specific biomedical applications of nitric oxide-releasing hydrogels are discussed.

Indexed as

antimicrobialbiomedicalhydrogelsnitric oxidewound healing

Identifiers

PMID37694274
PMCPMC10489397
OpenAlexW4376620255

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.